A review on aspects of diabetes mellitus caused by oxidative stress
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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10361-187352023-07-11T21:05:14Z A review on aspects of diabetes mellitus caused by oxidative stress Bhuiyan, Md. Rasshiq Amin Ashrafi, Sania Department of Pharmacy, Brac University Diabetes mellitus Oxidative stress Antioxidant Biomarkers Oxidative stress. Diabetes--Pathophysiology. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 41-47). As a result of constant exposure to various stimuli, the human body produces reactive species known as free radicals (ROS/RNS), which oxidize cellular components through the transfer of their free unpaired electrons. The body possesses endogenous antioxidant systems, or it acquires exogenous antioxidants from the diet to combat the harmful effects of such species. These antioxidants neutralize the harmful species and maintain the body's homeostasis. Any imbalance between RS and antioxidants causes oxidative stress, which in turn causes the emergence of pathological conditions, one of which is diabetes. The majority of research suggest that oxidative stress plays a role in the pathogenesis of diabetes through changes in enzymatic systems, lipid peroxidation, poor glutathione metabolism, and decreased levels of vitamin C. Different biomarkers of oxidative stress in diabetes mellitus include lipids, proteins, DNA damage, glutathione, catalase, and superoxide dismutase. Diabetes complications brought on by oxidative stress can include stroke, neuropathy, retinopathy, and nephropathy. This review's main goal was to briefly summarize the fundamentals of oxidative stress in diabetes mellitus and propose some natural remedies. Md. Rasshiq Amin Bhuiyan B. Pharmacy 2023-07-11T08:19:23Z 2023-07-11T08:19:23Z 2022 2022-12 Thesis ID: 17146042 http://hdl.handle.net/10361/18735 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 47 pages application/pdf Brac University |
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Brac University |
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Institutional Repository |
language |
English |
topic |
Diabetes mellitus Oxidative stress Antioxidant Biomarkers Oxidative stress. Diabetes--Pathophysiology. |
spellingShingle |
Diabetes mellitus Oxidative stress Antioxidant Biomarkers Oxidative stress. Diabetes--Pathophysiology. Bhuiyan, Md. Rasshiq Amin A review on aspects of diabetes mellitus caused by oxidative stress |
description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
author2 |
Ashrafi, Sania |
author_facet |
Ashrafi, Sania Bhuiyan, Md. Rasshiq Amin |
format |
Thesis |
author |
Bhuiyan, Md. Rasshiq Amin |
author_sort |
Bhuiyan, Md. Rasshiq Amin |
title |
A review on aspects of diabetes mellitus caused by oxidative stress |
title_short |
A review on aspects of diabetes mellitus caused by oxidative stress |
title_full |
A review on aspects of diabetes mellitus caused by oxidative stress |
title_fullStr |
A review on aspects of diabetes mellitus caused by oxidative stress |
title_full_unstemmed |
A review on aspects of diabetes mellitus caused by oxidative stress |
title_sort |
review on aspects of diabetes mellitus caused by oxidative stress |
publisher |
Brac University |
publishDate |
2023 |
url |
http://hdl.handle.net/10361/18735 |
work_keys_str_mv |
AT bhuiyanmdrasshiqamin areviewonaspectsofdiabetesmellituscausedbyoxidativestress AT bhuiyanmdrasshiqamin reviewonaspectsofdiabetesmellituscausedbyoxidativestress |
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