Application of cryo-EM method to study Covid-19 proteins
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2023
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| Διαθέσιμο Online: | http://hdl.handle.net/10361/18659 |
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10361-186592023-06-26T21:01:47Z Application of cryo-EM method to study Covid-19 proteins Akter, Farhana Sharmin, Sabrina Department of Pharmacy, Brac University Cryo-EM Covid-19 Corona viruses Vaccination SARS-CoV-2 Protein spikes Covid-19 (Disease) Coronavirus infections This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 41-44). Researchers from all around the globe are working quickly to utilize cryo-electron microscopy (cryo-EM) to explain how the corona virus disease (COVID-19) infects human cells, in tandem to the global community's efforts to stop the spread of the illness and cure individuals who have been diagnosed. Through the use of cryo-EM, these researchers were able to determine the spike protein's structural characteristics as well as that of the virus' cellular receptor. Cryo-EM, which studies the structure of physiologically significant molecules like proteins and pathogens at almost atomic resolution to easily grasp 3D structure and activity, has emerged in recent years as a popular and successful approach for biological research. The creation of vaccinations and the advancement of COVID-19 therapies will be facilitated and accelerated by these discoveries. Public access to the research team's cryo-EM structures is now possible. About seven years ago, cryo- EM began to be used more widely as improvements in electron detectors, software, productivity, and other critical elements made it possible for scientists to resolve crucial biological material at better resolution. A lot of work has been achieved in understanding the structure and dynamics of the corona virus in far less than two months. In the past, it may have taken years to advance to this level. This article will be reviewing the applications of the Cryogenic electron microscopy for studying and understanding the characteristics of protein spikes of the SARS-CoV-2, which can originate COVID-19 in the human body. Farhana Akter B. Pharmacy 2023-06-26T06:03:26Z 2023-06-26T06:03:26Z 2022 2022-10 Thesis ID 18346032 http://hdl.handle.net/10361/18659 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 56 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Cryo-EM Covid-19 Corona viruses Vaccination SARS-CoV-2 Protein spikes Covid-19 (Disease) Coronavirus infections |
| spellingShingle |
Cryo-EM Covid-19 Corona viruses Vaccination SARS-CoV-2 Protein spikes Covid-19 (Disease) Coronavirus infections Akter, Farhana Application of cryo-EM method to study Covid-19 proteins |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Sharmin, Sabrina |
| author_facet |
Sharmin, Sabrina Akter, Farhana |
| format |
Thesis |
| author |
Akter, Farhana |
| author_sort |
Akter, Farhana |
| title |
Application of cryo-EM method to study Covid-19 proteins |
| title_short |
Application of cryo-EM method to study Covid-19 proteins |
| title_full |
Application of cryo-EM method to study Covid-19 proteins |
| title_fullStr |
Application of cryo-EM method to study Covid-19 proteins |
| title_full_unstemmed |
Application of cryo-EM method to study Covid-19 proteins |
| title_sort |
application of cryo-em method to study covid-19 proteins |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/18659 |
| work_keys_str_mv |
AT akterfarhana applicationofcryoemmethodtostudycovid19proteins |
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1814309135906242560 |