A look into parkinson’s disease and the implications of gene therapy as a novel clinical approach
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2023
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Linkit: | http://hdl.handle.net/10361/18232 |
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10361-182322023-05-08T21:01:44Z A look into parkinson’s disease and the implications of gene therapy as a novel clinical approach Islam, Md. Rakibul Alam, Marzia Department of Pharmacy, Brac University Neurodegenerative disorder Levodopa Gene therapy Dopamine replacement therapy Parkinson’s disease This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 46-47). "Parkinson’s Disease (PD) is considered as one of the highest occurring neurodegenerative disorders. Motor complexities are the major symptoms of this disease which mainly includes bradykinesia, rigidity and tremor. Moreover, the non-motor symptoms can be included as mental and psychological complexities. Injury to the dopamine pathways is considered as the primary pathological reason of PD. Although the older population represents the majority of the patients, 5- 10% of the patients are relatively younger. Currently, dopamine replacement therapy with levodopa is the most common mode of treatment for alleviating the symptoms and retaining the functional capabilities. Here, gene therapy can be a viable treatment approach for such neurodegenerative disorders since it serves by knocking down the pathological genes. Even though few questions are yet to be answered before incorporating gene therapy in Parkinson’s disease, this novel therapeutic method has the potential to reshape the future of neurologic therapeutics." Md. Rakibul Islam B. Pharmacy 2023-05-08T03:48:34Z 2023-05-08T03:48:34Z 2022 2022-02 Thesis ID 16146056 http://hdl.handle.net/10361/18232 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 47 pages application/pdf Brac University |
institution |
Brac University |
collection |
Institutional Repository |
language |
English |
topic |
Neurodegenerative disorder Levodopa Gene therapy Dopamine replacement therapy Parkinson’s disease |
spellingShingle |
Neurodegenerative disorder Levodopa Gene therapy Dopamine replacement therapy Parkinson’s disease Islam, Md. Rakibul A look into parkinson’s disease and the implications of gene therapy as a novel clinical approach |
description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
author2 |
Alam, Marzia |
author_facet |
Alam, Marzia Islam, Md. Rakibul |
format |
Thesis |
author |
Islam, Md. Rakibul |
author_sort |
Islam, Md. Rakibul |
title |
A look into parkinson’s disease and the implications of gene therapy as a novel clinical approach |
title_short |
A look into parkinson’s disease and the implications of gene therapy as a novel clinical approach |
title_full |
A look into parkinson’s disease and the implications of gene therapy as a novel clinical approach |
title_fullStr |
A look into parkinson’s disease and the implications of gene therapy as a novel clinical approach |
title_full_unstemmed |
A look into parkinson’s disease and the implications of gene therapy as a novel clinical approach |
title_sort |
look into parkinson’s disease and the implications of gene therapy as a novel clinical approach |
publisher |
Brac University |
publishDate |
2023 |
url |
http://hdl.handle.net/10361/18232 |
work_keys_str_mv |
AT islammdrakibul alookintoparkinsonsdiseaseandtheimplicationsofgenetherapyasanovelclinicalapproach AT islammdrakibul lookintoparkinsonsdiseaseandtheimplicationsofgenetherapyasanovelclinicalapproach |
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1814309213363503104 |