Role of voltage-gated sodium channel modulators in peripheral nervous system disorders
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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| स्वरूप: | थीसिस |
| भाषा: | English |
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Brac University
2023
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| ऑनलाइन पहुंच: | http://hdl.handle.net/10361/18064 |
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10361-18064 |
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10361-180642023-04-03T21:01:50Z Role of voltage-gated sodium channel modulators in peripheral nervous system disorders Mithila, Sabekun Nahar Kabir, Md. Tanvir Department of Pharmacy, Brac University VGSC Peripheral nervous system disorders Voltage-gated sodium channel modulators Marine. Nervous system--Diseases. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 39-48). In current therapy for controlling peripheral nervous system disorders, one of the milestones is the voltage-gated sodium channel modulators. They have higher efficacy with improved side effects. They target the channel and their different subunits to modify the nerve impulse by allowing sodium ions. Selective drugs and biological products are used as modulators to limit the negative effects of disorders. Some drugs may either activate or deactivate the channels by altering the voltage-gated sodium channels pore. Moreover, biological products like alkaloids, marine toxins have a crucial role in understanding binding sites with actions on the sodium channel. Researchers are investigating numerous isoform-selective drugs in treating peripheral nervous system-related disorders. In this report, detailed information about the modulator's ongoing research on the active field is also elucidated. Sabekun Nahar Mithila B. Pharmacy 2023-04-03T06:47:39Z 2023-04-03T06:47:39Z 2022 2022-02 Thesis ID: 17146031 http://hdl.handle.net/10361/18064 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 48 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
VGSC Peripheral nervous system disorders Voltage-gated sodium channel modulators Marine. Nervous system--Diseases. |
| spellingShingle |
VGSC Peripheral nervous system disorders Voltage-gated sodium channel modulators Marine. Nervous system--Diseases. Mithila, Sabekun Nahar Role of voltage-gated sodium channel modulators in peripheral nervous system disorders |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Kabir, Md. Tanvir |
| author_facet |
Kabir, Md. Tanvir Mithila, Sabekun Nahar |
| format |
Thesis |
| author |
Mithila, Sabekun Nahar |
| author_sort |
Mithila, Sabekun Nahar |
| title |
Role of voltage-gated sodium channel modulators in peripheral nervous system disorders |
| title_short |
Role of voltage-gated sodium channel modulators in peripheral nervous system disorders |
| title_full |
Role of voltage-gated sodium channel modulators in peripheral nervous system disorders |
| title_fullStr |
Role of voltage-gated sodium channel modulators in peripheral nervous system disorders |
| title_full_unstemmed |
Role of voltage-gated sodium channel modulators in peripheral nervous system disorders |
| title_sort |
role of voltage-gated sodium channel modulators in peripheral nervous system disorders |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/18064 |
| work_keys_str_mv |
AT mithilasabekunnahar roleofvoltagegatedsodiumchannelmodulatorsinperipheralnervoussystemdisorders |
| _version_ |
1814308246125543424 |