Dendritic cell vaccine for the treatment of cancer
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2023
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| ऑनलाइन पहुंच: | http://hdl.handle.net/10361/17765 |
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10361-177652023-01-18T21:01:48Z Dendritic cell vaccine for the treatment of cancer Haque, Tanzila Alam, Ms. Marzia Department of Pharmacy, Brac University DCexos Plasmacytoid DC Dendritic cell Immunity Immunotherapy. Cancer--Treatment. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 32-38). Dendritic cells (DCs) serve as sentinels for the immune system, antigen-specific immune responses are initiated and regulated. Cross-priming, a mechanism in which DCs activate CD8 T cells by presenting external antigens to their major histocompatibility complex is crucial for CD8 T cell immunity and tolerance. Immunosuppression caused by tumors and the functional restriction of routinely utilized dendritic cells generated from monocytes are two important obstacles to the effectiveness of DC-based vaccinations. Exosomes generated from DC have piqued interest as cell-free therapeutic agents due to being inert vesicles, they are resistant to tumor-mediated suppression. Another fascinating breakthrough is the utilization of DCs that circulate naturally rather than in vitro grown DCs, which has demonstrated encouraging effects in clinical trials with both human blood cyclin dependent kinase and plasmacytoid DCs. Tanzila Haque B. Pharmacy 2023-01-18T09:57:24Z 2023-01-18T09:57:24Z 2022 2022-02 Thesis ID: 18146090 http://hdl.handle.net/10361/17765 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 38 Pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
en_US |
| topic |
DCexos Plasmacytoid DC Dendritic cell Immunity Immunotherapy. Cancer--Treatment. |
| spellingShingle |
DCexos Plasmacytoid DC Dendritic cell Immunity Immunotherapy. Cancer--Treatment. Haque, Tanzila Dendritic cell vaccine for the treatment of cancer |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Alam, Ms. Marzia |
| author_facet |
Alam, Ms. Marzia Haque, Tanzila |
| format |
Thesis |
| author |
Haque, Tanzila |
| author_sort |
Haque, Tanzila |
| title |
Dendritic cell vaccine for the treatment of cancer |
| title_short |
Dendritic cell vaccine for the treatment of cancer |
| title_full |
Dendritic cell vaccine for the treatment of cancer |
| title_fullStr |
Dendritic cell vaccine for the treatment of cancer |
| title_full_unstemmed |
Dendritic cell vaccine for the treatment of cancer |
| title_sort |
dendritic cell vaccine for the treatment of cancer |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/17765 |
| work_keys_str_mv |
AT haquetanzila dendriticcellvaccineforthetreatmentofcancer |
| _version_ |
1814308899019292672 |