The basics of Axon guidance: Role of Netrin, SHH, BMP and Ephrin
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2022.
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Brac University
2023
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| 在线阅读: | http://hdl.handle.net/10361/17742 |
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10361-177422023-02-16T10:08:30Z The basics of Axon guidance: Role of Netrin, SHH, BMP and Ephrin Binte Sayed Prapty, Chowdhury Nusaiba A-Afrin, Noor Dey, Moumita Bin Naser, Iftekhar Department of Mathematics and Natural Sciences, Brac University Axon Guidance Netrin SHH BMP Ephrin Nervous System--anatomy & histology This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2022. Catalogued from PDF version of thesis. Includes bibliographical references (pages 35-42). Neurons navigate through tissues, over both long and short distances, to locate their target synaptic partners, forming the neural circuit. Specific guidance cues belonging to highly conserved families direct the neurons through their axons along specific pathways by attractive and repulsive actions. These guidance systems create a surprisingly diverse set of neuronal circuits, in the: spinal cord, forebrain, and retinotopic organization. The exact dynamics of the growth cones while navigating through the signaling pathways are not thoroughly understood, only the major mechanisms and proteins commonly found are recognized. The role of several extracellular receptors and ligands in the process has also been identified. Having bifunctional molecules acting as both growth-inductive and inhibitory cues, axon guidance remains a complex process with immediate as well as long-term visible consequences in the form of neural disorders leading to many diseases. The overall mechanism with four of the key molecules that guide this pathfinding in three separate commissures are the topics of this review. Chowdhury Nusaiba Binte Sayed Prapty Noor-A-Afrin Moumita Dey B. Biotechnology 2023-01-17T09:09:25Z 2023-01-17T09:09:25Z 2022 2022-04 Thesis ID: 17236011 ID: 17236007 ID: 18136044 http://hdl.handle.net/10361/17742 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 42 Pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Axon Guidance Netrin SHH BMP Ephrin Nervous System--anatomy & histology |
| spellingShingle |
Axon Guidance Netrin SHH BMP Ephrin Nervous System--anatomy & histology Binte Sayed Prapty, Chowdhury Nusaiba A-Afrin, Noor Dey, Moumita The basics of Axon guidance: Role of Netrin, SHH, BMP and Ephrin |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2022. |
| author2 |
Bin Naser, Iftekhar |
| author_facet |
Bin Naser, Iftekhar Binte Sayed Prapty, Chowdhury Nusaiba A-Afrin, Noor Dey, Moumita |
| format |
Thesis |
| author |
Binte Sayed Prapty, Chowdhury Nusaiba A-Afrin, Noor Dey, Moumita |
| author_sort |
Binte Sayed Prapty, Chowdhury Nusaiba |
| title |
The basics of Axon guidance: Role of Netrin, SHH, BMP and Ephrin |
| title_short |
The basics of Axon guidance: Role of Netrin, SHH, BMP and Ephrin |
| title_full |
The basics of Axon guidance: Role of Netrin, SHH, BMP and Ephrin |
| title_fullStr |
The basics of Axon guidance: Role of Netrin, SHH, BMP and Ephrin |
| title_full_unstemmed |
The basics of Axon guidance: Role of Netrin, SHH, BMP and Ephrin |
| title_sort |
basics of axon guidance: role of netrin, shh, bmp and ephrin |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/17742 |
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