Horizontal gene transfer: an insight into antimicrobial resistance
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2022.
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| التنسيق: | أطروحة |
| اللغة: | English |
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Brac University
2023
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10361/17701 |
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10361-17701 |
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10361-177012023-01-16T04:57:26Z Horizontal gene transfer: an insight into antimicrobial resistance Tanveer, Mahbubul Hoque Rafa, Atihar Arzu Sharma, Arnob Islam, Tashfia Naser, Iftekhar Bin Department of Mathematics and Natural Sciences, Brac University Antibiotics Antibiotic resistance Horizontal Gene Transfer (HGT) Drug resistance in microorganisms Anti-infective agents This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2022. Catalogued from PDF version of thesis. Includes bibliographical references (pages 62-84). Antimicrobial resistance (AMR), which affects a variety of infectious pathogens, is a pivotal public health issue for many countries and corporations. Governments across the globe are starting to take heed of an issue that is so grave that it jeopardizes the advancements of advanced medication such as antibiotics. A key factor in the spread of antibiotic resistance is horizontal gene transfer (HGT). Contrarily, it is periodically presumed that antibiotics stimulate HGT. A comprehensive review of the research, however, indicates that there is insufficient credible data available to support such a hypothesis in principle. This is primarily due to the insufficiency of concise quantitative studies to answer this query. We assess how significantly HGT correlates to the antibiotic resistance spread in this study, as well as what is documented about how antibiotics regulate the mechanics of HGT. Our attention is on conjugation, the predominant HGT method that is primarily responsible for the global spread of antibiotic resistance. According to our research results, trials to quantify HGT must be planned in a systematic way in order to critically evaluate the outcomes. Such experiments are crucial for constructing cutting-edge approaches to inhibit the propagation of resistance by HGT. In this study, we explore about how much HGT contributes to the spread of antibiotic resistance and explore what is known about how antibiotics affect the dynamics of HGT including a brief discussion on antibiotic resistome. Mahbubul Hoque Tanveer Atihar Arzu Rafa Arnob Sharma Tashfia Islam B. Biotechnology 2023-01-09T09:29:02Z 2023-01-09T09:29:02Z 2022 2022-10 Thesis ID 18136008 ID 18336027 ID 18136054 ID 19136059 http://hdl.handle.net/10361/17701 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 84 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Antibiotics Antibiotic resistance Horizontal Gene Transfer (HGT) Drug resistance in microorganisms Anti-infective agents |
| spellingShingle |
Antibiotics Antibiotic resistance Horizontal Gene Transfer (HGT) Drug resistance in microorganisms Anti-infective agents Tanveer, Mahbubul Hoque Rafa, Atihar Arzu Sharma, Arnob Islam, Tashfia Horizontal gene transfer: an insight into antimicrobial resistance |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2022. |
| author2 |
Naser, Iftekhar Bin |
| author_facet |
Naser, Iftekhar Bin Tanveer, Mahbubul Hoque Rafa, Atihar Arzu Sharma, Arnob Islam, Tashfia |
| format |
Thesis |
| author |
Tanveer, Mahbubul Hoque Rafa, Atihar Arzu Sharma, Arnob Islam, Tashfia |
| author_sort |
Tanveer, Mahbubul Hoque |
| title |
Horizontal gene transfer: an insight into antimicrobial resistance |
| title_short |
Horizontal gene transfer: an insight into antimicrobial resistance |
| title_full |
Horizontal gene transfer: an insight into antimicrobial resistance |
| title_fullStr |
Horizontal gene transfer: an insight into antimicrobial resistance |
| title_full_unstemmed |
Horizontal gene transfer: an insight into antimicrobial resistance |
| title_sort |
horizontal gene transfer: an insight into antimicrobial resistance |
| publisher |
Brac University |
| publishDate |
2023 |
| url |
http://hdl.handle.net/10361/17701 |
| work_keys_str_mv |
AT tanveermahbubulhoque horizontalgenetransferaninsightintoantimicrobialresistance AT rafaatihararzu horizontalgenetransferaninsightintoantimicrobialresistance AT sharmaarnob horizontalgenetransferaninsightintoantimicrobialresistance AT islamtashfia horizontalgenetransferaninsightintoantimicrobialresistance |
| _version_ |
1814308760245501952 |