Cryo-EM in COVID-19 drug invention and discovery
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2022
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| ऑनलाइन पहुंच: | http://hdl.handle.net/10361/17583 |
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10361-175832022-11-17T21:01:37Z Cryo-EM in COVID-19 drug invention and discovery Trisha, Rabeya Rahman Yasmin, Hasina Department of Pharmacy, Brac University Drug Discovery Cryo-EM SARS-CoV-2 COVID-19 Drug-Protein interactions Electron microscopy--Technique This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 31-40). Cryo-EM is a type of electron microscope that employs the cryomicroscopy technology, which involves cooling materials and examining them under a microscope to create 3D models of proteins. Throughout this COVID-19 pandemic, the development of medicines are critical, and the protein structures of the SARS-CoV-2 virus must be recognized in order to battle COVID 19. Cryo-EM may be used to find protein structural alignments, protein positioning, domain motif interaction with known antiviral medications, and potential therapeutic routes for creating treatments and vaccines. Furthermore, because Cryo-EM allows scientists to examine dynamic models of proteins, it makes it simpler for them to analyze molecules of various shapes and dimensions, which may be a significant benefit over X-ray crystallography. The use of Cryo-EM in medication development for COVID-19 including how future drugs can be designed to counter COVID-19 are discussed in this review paper so that the pandemic can be brought to a close. Rabeya Rahman Trisha B. Pharmacy 2022-11-17T06:17:46Z 2022-11-17T06:17:46Z 2022 2022-03 Thesis ID: 17346017 http://hdl.handle.net/10361/17583 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 40 Pages application/pdf Brac University |
| institution |
Brac University |
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Institutional Repository |
| language |
en_US |
| topic |
Drug Discovery Cryo-EM SARS-CoV-2 COVID-19 Drug-Protein interactions Electron microscopy--Technique |
| spellingShingle |
Drug Discovery Cryo-EM SARS-CoV-2 COVID-19 Drug-Protein interactions Electron microscopy--Technique Trisha, Rabeya Rahman Cryo-EM in COVID-19 drug invention and discovery |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Yasmin, Hasina |
| author_facet |
Yasmin, Hasina Trisha, Rabeya Rahman |
| format |
Thesis |
| author |
Trisha, Rabeya Rahman |
| author_sort |
Trisha, Rabeya Rahman |
| title |
Cryo-EM in COVID-19 drug invention and discovery |
| title_short |
Cryo-EM in COVID-19 drug invention and discovery |
| title_full |
Cryo-EM in COVID-19 drug invention and discovery |
| title_fullStr |
Cryo-EM in COVID-19 drug invention and discovery |
| title_full_unstemmed |
Cryo-EM in COVID-19 drug invention and discovery |
| title_sort |
cryo-em in covid-19 drug invention and discovery |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/17583 |
| work_keys_str_mv |
AT trisharabeyarahman cryoemincovid19druginventionanddiscovery |
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