Harnessing exosomes as a drug delivery system for neurodegenerative diseases
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021.
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Brac University
2022
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| Online Erişim: | http://hdl.handle.net/10361/17575 |
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10361-17575 |
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10361-175752022-11-16T21:01:37Z Harnessing exosomes as a drug delivery system for neurodegenerative diseases Ferdous, Farhana Azad, Dr. Md Abul Kalam Department of Pharmacy, Brac University Exosomes Nano-vesicles Transfer of pathogens Neurodegenerative Diseases Natural delivery vehicles Nervous system--Degeneration Drug delivery systems This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 38-47). Exosomes are recently discovered bilayer containing membrane which are small-sized (30- 100mm) nanovesicles that are formed due to the fusion of multivesicular bodies with the plasma membrane. Exosomes are involved in a number of functions including cell to cell signaling, unwanted proteins removal and pathogen transfer between cells. Exosomes are involved in promoting pathways of neurodegenerative diseases such as in Alzheimer's disease (beta-amyloid peptide), in Parkinson's disease (alpha-synuclein) and so on. All the exosomes take part in such enervative neuropathology, one encouraging aspect of exosomes is the development of a methodology to use these as natural delivery vehicles for therapeutics. Established characteristics including the blood-brain barrier crossing ability, half-life span, and stability compel it as an effective drug delivery system. The main focus of this review is the impact of exosomes in neurodegenerative diseases and disclose their probable role as a therapeutic tool for delivering drugs. Farhana Ferdous B. Pharmacy 2022-11-16T04:28:27Z 2022-11-16T04:28:27Z 2021 2021-08 Thesis ID: 16346043 http://hdl.handle.net/10361/17575 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 47 Pages application/pdf Brac University |
| institution |
Brac University |
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Institutional Repository |
| language |
en_US |
| topic |
Exosomes Nano-vesicles Transfer of pathogens Neurodegenerative Diseases Natural delivery vehicles Nervous system--Degeneration Drug delivery systems |
| spellingShingle |
Exosomes Nano-vesicles Transfer of pathogens Neurodegenerative Diseases Natural delivery vehicles Nervous system--Degeneration Drug delivery systems Ferdous, Farhana Harnessing exosomes as a drug delivery system for neurodegenerative diseases |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. |
| author2 |
Azad, Dr. Md Abul Kalam |
| author_facet |
Azad, Dr. Md Abul Kalam Ferdous, Farhana |
| format |
Thesis |
| author |
Ferdous, Farhana |
| author_sort |
Ferdous, Farhana |
| title |
Harnessing exosomes as a drug delivery system for neurodegenerative diseases |
| title_short |
Harnessing exosomes as a drug delivery system for neurodegenerative diseases |
| title_full |
Harnessing exosomes as a drug delivery system for neurodegenerative diseases |
| title_fullStr |
Harnessing exosomes as a drug delivery system for neurodegenerative diseases |
| title_full_unstemmed |
Harnessing exosomes as a drug delivery system for neurodegenerative diseases |
| title_sort |
harnessing exosomes as a drug delivery system for neurodegenerative diseases |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/17575 |
| work_keys_str_mv |
AT ferdousfarhana harnessingexosomesasadrugdeliverysystemforneurodegenerativediseases |
| _version_ |
1814308975166881792 |