CNS Depressant Activity of Various Parts of Heritiera fomes
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2022
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| Online Access: | http://hdl.handle.net/10361/17565 |
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10361-175652022-11-15T21:01:40Z CNS Depressant Activity of Various Parts of Heritiera fomes Taslim, Umiya Ripa, Dr. Farhana Alam Department of Pharmacy, Brac University Heritiera fomes Diazepam CNS Depressant Hole cross method Open field method. Heritiera fomes This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 46-50). Heritiera fomes (Family: Malvaceae) is usually known as “Sundori tree” in Bangladesh. The plant is used in pain, gastrointestinal problems, goiter, fever, diabetes etc. The present investigation was undertaken which deals with the central nervous system (CNS) depressant activity of ethanol extract of H.fomes in mice models. The central nervous system (CNS) depressant activity of H.fomes was evaluated by the classical models of depression as open field, hole cross tests in mice. The animals were divided into eight groups containing five mice each. The test groups received extract at the doses of 250 mg/kg and 500 mg/kg body weight orally whereas the control group received distilled water (10 mL/kg, p.o.). Diazepam (1 mg/kg, p.o.) was used as standard drug. The plant extract significantly decreased the locomotor activity of mice in open field and hole cross tests when compared to the control (p < 0.05). It is observed that the extract showed significantly (p < 0.05) increased in immobility time force. The present work depicts the possible CNS depressant activity of H.fomes in mice models. The obtained results provide support for the use of this species in traditional medicine and warrants further pharmacological investigations that could lead to novel leads in future. Umiya Taslim B. Pharmacy 2022-11-15T04:53:10Z 2022-11-15T04:53:10Z 2022 2022-03 Thesis ID: 18146066 http://hdl.handle.net/10361/17565 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 50 Pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
en_US |
| topic |
Heritiera fomes Diazepam CNS Depressant Hole cross method Open field method. Heritiera fomes |
| spellingShingle |
Heritiera fomes Diazepam CNS Depressant Hole cross method Open field method. Heritiera fomes Taslim, Umiya CNS Depressant Activity of Various Parts of Heritiera fomes |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Ripa, Dr. Farhana Alam |
| author_facet |
Ripa, Dr. Farhana Alam Taslim, Umiya |
| format |
Thesis |
| author |
Taslim, Umiya |
| author_sort |
Taslim, Umiya |
| title |
CNS Depressant Activity of Various Parts of Heritiera fomes |
| title_short |
CNS Depressant Activity of Various Parts of Heritiera fomes |
| title_full |
CNS Depressant Activity of Various Parts of Heritiera fomes |
| title_fullStr |
CNS Depressant Activity of Various Parts of Heritiera fomes |
| title_full_unstemmed |
CNS Depressant Activity of Various Parts of Heritiera fomes |
| title_sort |
cns depressant activity of various parts of heritiera fomes |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/17565 |
| work_keys_str_mv |
AT taslimumiya cnsdepressantactivityofvariouspartsofheritierafomes |
| _version_ |
1814307276668796928 |