Targeted therapeutic options in the treatment of Breast Cancer
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2022
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| Acesso em linha: | http://hdl.handle.net/10361/17562 |
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10361-175622022-11-15T21:01:37Z Targeted therapeutic options in the treatment of Breast Cancer Alam, Kazi Tasnuva Kabir, Dr. Eva Rahman Department of Pharmacy, Brac University Breast cancer Targeted therapy Biologics Biosimilars HER2 Trastuzumab Breast--Cancer--Patients Breast--Cancer--Treatment This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 35-48). The recent application of targeted therapies such as biologics, biosimilars, and other targeted biological agents in the treatment of diverse subtypes of breast cancer has been facilitated by the decoding of the human genome and the subdivision of breast cancer on a molecular level. This review focuses on targeted therapeutic approaches used in breast cancer therapy, such as anti-HER2 targeted monoclonal antibodies, CDK4/6 inhibitors, immune checkpoint inhibitors, blockers of the PI3K/AKT/mTOR signaling pathways, PARP inhibitors, Antibody-Drug Conjugates (ADCs), and anti-VEGF agents. Moreover, this paper specifically discusses the role of trastuzumab in the treatment of HER2-positive breast tumors, as well as its approved biosimilars which aim to make breast cancer treatment affordable, while preventing cancer recurrence and improving overall therapeutic efficacy Kazi Tasnuva Alam B. Pharmacy 2022-11-15T03:55:22Z 2022-11-15T03:55:22Z 2022 2022-02 Thesis ID: 18146028 http://hdl.handle.net/10361/17562 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 48 Pages application/pdf Brac University |
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Brac University |
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Institutional Repository |
| language |
en_US |
| topic |
Breast cancer Targeted therapy Biologics Biosimilars HER2 Trastuzumab Breast--Cancer--Patients Breast--Cancer--Treatment |
| spellingShingle |
Breast cancer Targeted therapy Biologics Biosimilars HER2 Trastuzumab Breast--Cancer--Patients Breast--Cancer--Treatment Alam, Kazi Tasnuva Targeted therapeutic options in the treatment of Breast Cancer |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Kabir, Dr. Eva Rahman |
| author_facet |
Kabir, Dr. Eva Rahman Alam, Kazi Tasnuva |
| format |
Thesis |
| author |
Alam, Kazi Tasnuva |
| author_sort |
Alam, Kazi Tasnuva |
| title |
Targeted therapeutic options in the treatment of Breast Cancer |
| title_short |
Targeted therapeutic options in the treatment of Breast Cancer |
| title_full |
Targeted therapeutic options in the treatment of Breast Cancer |
| title_fullStr |
Targeted therapeutic options in the treatment of Breast Cancer |
| title_full_unstemmed |
Targeted therapeutic options in the treatment of Breast Cancer |
| title_sort |
targeted therapeutic options in the treatment of breast cancer |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/17562 |
| work_keys_str_mv |
AT alamkazitasnuva targetedtherapeuticoptionsinthetreatmentofbreastcancer |
| _version_ |
1814307806648467456 |