Screening of anthelmintic activity of Heritiera fomes
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2022
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| Online Access: | http://hdl.handle.net/10361/17310 |
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10361-173102022-09-26T21:02:07Z Screening of anthelmintic activity of Heritiera fomes Riya, Fahmida Haque Ripa, Farhana Alam Department of Pharmacy, Brac University Heritiera fomes Anthelmintic activity Helminths Albendazole Tween 20 Pheretima posthuma Heritiera fomes This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 49-56). Heritiera fomes is a mangrove medicinal plant which is rich of ethnomedicinal usage against helminths. At present, it is found that H. fomes is a good reservoir of compounds such as phenols, tannin, alkaloids which have the possibility to be a better source to treat helminthiasis in living organism which is a great motivation to work on this research. The moto of this finding is to check in vitro anthelmintic activity of different parts (leaf, bark, root) of H. fomes on Bangladeshi earthworms Pheretima posthuma. Albendazole was used as standard drug to compare the test result. Anthelmintic activity was showed by three concentrations of H. fomes (25mg/ml, 50mg/ml and 75mg/ml) of each extract in a dose dependent inhibition. The results have been interpreted as paralysis time and death time of the earth worms. From the obtained result it was found that bark extracts of H. fomes exhibited significant anthelmintic activity at the concentration of 75mg/ml where the paralysis time and death time of the worms is 37.67±2.52 min and 47.67±3.51 min respectively, compared to the standard albendazole. This study encapsulates the significance of H. fomes in the use for anthelmintic activity and requirement further investigation for the isolation of active constituent which is responsible for the anthelmintic activity. Fahmida Haque Riya B. Pharmacy 2022-09-26T07:07:23Z 2022-09-26T07:07:23Z 2022 2022-03 Thesis ID 18146048 http://hdl.handle.net/10361/17310 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 56 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Heritiera fomes Anthelmintic activity Helminths Albendazole Tween 20 Pheretima posthuma Heritiera fomes |
| spellingShingle |
Heritiera fomes Anthelmintic activity Helminths Albendazole Tween 20 Pheretima posthuma Heritiera fomes Riya, Fahmida Haque Screening of anthelmintic activity of Heritiera fomes |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Ripa, Farhana Alam |
| author_facet |
Ripa, Farhana Alam Riya, Fahmida Haque |
| format |
Thesis |
| author |
Riya, Fahmida Haque |
| author_sort |
Riya, Fahmida Haque |
| title |
Screening of anthelmintic activity of Heritiera fomes |
| title_short |
Screening of anthelmintic activity of Heritiera fomes |
| title_full |
Screening of anthelmintic activity of Heritiera fomes |
| title_fullStr |
Screening of anthelmintic activity of Heritiera fomes |
| title_full_unstemmed |
Screening of anthelmintic activity of Heritiera fomes |
| title_sort |
screening of anthelmintic activity of heritiera fomes |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/17310 |
| work_keys_str_mv |
AT riyafahmidahaque screeningofanthelminticactivityofheritierafomes |
| _version_ |
1814308897853276160 |