Application of microRNA (miRNA) in Alzheimer’s Disease (AD)
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
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Brac University
2022
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| Accès en ligne: | http://hdl.handle.net/10361/17307 |
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10361-173072022-09-26T21:02:05Z Application of microRNA (miRNA) in Alzheimer’s Disease (AD) Halim, Rabea Yasmin, Hasina Department of Pharmacy, Brac University MicroRNA Beta-amyloid Tau protein Synapse Alzheimer’s disease This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 45-48). Alzheimer's disease is a fatal illness that primarily affects older generations; its pathology pathways include beta-amyloid, tau protein, and activated microglia, destruction of synapse and no disease-modifying medication has been found. MicroRNA has the potential to be a novel therapeutic method by targeting certain mRNAs that cause the disease to worsen, so their overexpression causes a reduction in disease, and another class of microRNA targets those mRNAs that are required for a healthy brain, but their overexpression causes the disease to worsen. There are several microRNAs, and each one has a different target and impact in the brain, with some having a therapeutic effect and others having a pathogenic effect. MicroRNA is a promising therapeutic agent and drug target which needs to be implemented in human trials, not just animal models. Rabea Halim B. Pharmacy 2022-09-26T06:10:13Z 2022-09-26T06:10:13Z 2022 2022-03 Thesis ID 18146006 http://hdl.handle.net/10361/17307 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 48 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
MicroRNA Beta-amyloid Tau protein Synapse Alzheimer’s disease |
| spellingShingle |
MicroRNA Beta-amyloid Tau protein Synapse Alzheimer’s disease Halim, Rabea Application of microRNA (miRNA) in Alzheimer’s Disease (AD) |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. |
| author2 |
Yasmin, Hasina |
| author_facet |
Yasmin, Hasina Halim, Rabea |
| format |
Thesis |
| author |
Halim, Rabea |
| author_sort |
Halim, Rabea |
| title |
Application of microRNA (miRNA) in Alzheimer’s Disease (AD) |
| title_short |
Application of microRNA (miRNA) in Alzheimer’s Disease (AD) |
| title_full |
Application of microRNA (miRNA) in Alzheimer’s Disease (AD) |
| title_fullStr |
Application of microRNA (miRNA) in Alzheimer’s Disease (AD) |
| title_full_unstemmed |
Application of microRNA (miRNA) in Alzheimer’s Disease (AD) |
| title_sort |
application of microrna (mirna) in alzheimer’s disease (ad) |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/17307 |
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AT halimrabea applicationofmicrornamirnainalzheimersdiseasead |
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1814309132534022144 |