Recent advances in Cancer treatment targeting autophagy and future aspects

This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.

Bibliografische gegevens
Hoofdauteur:	Emon, Kamrul Hasan
Andere auteurs:	Sharmin, Sabrina
Formaat:	Thesis
Taal:	English
Gepubliceerd in:	Brac University 2022
Onderwerpen:	Autophagy Autophagic cell death Anticancer therapy Chemotherapy Autophagy inhibitors Cell death Lysosomes Cancer > Treatment
Online toegang:	http://hdl.handle.net/10361/17247

id	10361-17247
record_format	dspace
spelling	10361-172472022-09-21T21:01:37Z Recent advances in Cancer treatment targeting autophagy and future aspects Emon, Kamrul Hasan Sharmin, Sabrina Department of Pharmacy, Brac University Autophagy Autophagic cell death Anticancer therapy Chemotherapy Autophagy inhibitors Cell death Lysosomes Cancer--Treatment This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 31-55). Lysosomal autophagy controls cellular homeostasis by degrading and recycling cytoplasmic molecules and organelles in the lysosome. This process in neuronal cells protects cognitive decline by removing abnormal intracellular protein accumulation. Since autophagy is well-known, new regulators of the process are expected to be discovered. It has been hypothesized that modulating autophagy can be employed as a therapeutic mechanism to boost the efficacy of traditional medicines, such as chemotherapy and radiation therapy. Thus, a critical concern in cancer therapy is whether to promote or inhibit autophagy. To enable the successful development of treatments targeting autophagy, a complete knowledge of the molecular components of autophagy is addressed here, with a particular emphasis on druggable targets, combination therapy are also explored as well as the possible hurdles and constraints for the application of these innovative therapeutic techniques in clinical practice. Kamrul Hasan Emon B. Pharmacy 2022-09-21T04:14:40Z 2022-09-21T04:14:40Z 2022 2022-03 Thesis ID 18146020 http://hdl.handle.net/10361/17247 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 55 pages application/pdf Brac University
institution	Brac University
collection	Institutional Repository
language	English
topic	Autophagy Autophagic cell death Anticancer therapy Chemotherapy Autophagy inhibitors Cell death Lysosomes Cancer--Treatment
spellingShingle	Autophagy Autophagic cell death Anticancer therapy Chemotherapy Autophagy inhibitors Cell death Lysosomes Cancer--Treatment Emon, Kamrul Hasan Recent advances in Cancer treatment targeting autophagy and future aspects
description	This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2022.
author2	Sharmin, Sabrina
author_facet	Sharmin, Sabrina Emon, Kamrul Hasan
format	Thesis
author	Emon, Kamrul Hasan
author_sort	Emon, Kamrul Hasan
title	Recent advances in Cancer treatment targeting autophagy and future aspects
title_short	Recent advances in Cancer treatment targeting autophagy and future aspects
title_full	Recent advances in Cancer treatment targeting autophagy and future aspects
title_fullStr	Recent advances in Cancer treatment targeting autophagy and future aspects
title_full_unstemmed	Recent advances in Cancer treatment targeting autophagy and future aspects
title_sort	recent advances in cancer treatment targeting autophagy and future aspects
publisher	Brac University
publishDate	2022
url	http://hdl.handle.net/10361/17247
work_keys_str_mv	AT emonkamrulhasan recentadvancesincancertreatmenttargetingautophagyandfutureaspects
_version_	1814309644591431680

Recent advances in Cancer treatment targeting autophagy and future aspects

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