Prospective detection methods for Tau protein: an important biomarker for Alzheimer’s disease
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021.
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Brac University
2022
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| 在线阅读: | http://hdl.handle.net/10361/17191 |
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10361-171912022-09-11T21:01:41Z Prospective detection methods for Tau protein: an important biomarker for Alzheimer’s disease Afra, Sumaiya Yasmin, Hasina Department of Pharmacy, Brac University Alzheimer’s disease Tau protein Surface plasmon resonance Enzyme-linked immunosorbent assay Quartz crystal microbalance Alzheimer's disease--Diagnosis Proteins This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. Cataloged from PDF version of thesis. Includes bibliographical references (pages 46-57). Tau protein is one of the keystones in the diagnosis of Alzheimer’s disease. The modern detection techniques have come up to visualize, track and assess tau pathology and have further contributed with information about tau deposition in human brain. The commercially available techniques include PET scan, digitalized enzyme-linked immunosorbent assay, Biolayer interferometry. However, each of the techniques has its own limitations such as tracers binding to off target, higher chances of cross reaction. This report has detailed the information about the active field of ongoing research methods to detect tau protein such as Surface plasmon resonance, Quartz crystal microbalance, Surface-enhanced Raman scattering based sandwich assay along with their selectivity. Hence, all of these techniques can be used to detect the inhibitors that target tau protein deposits or phosphorylates. Sumaiya Afra B. Pharmacy 2022-09-11T06:00:31Z 2022-09-11T06:00:31Z 2021 2021-11 Thesis ID 17146058 http://hdl.handle.net/10361/17191 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 57 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Alzheimer’s disease Tau protein Surface plasmon resonance Enzyme-linked immunosorbent assay Quartz crystal microbalance Alzheimer's disease--Diagnosis Proteins |
| spellingShingle |
Alzheimer’s disease Tau protein Surface plasmon resonance Enzyme-linked immunosorbent assay Quartz crystal microbalance Alzheimer's disease--Diagnosis Proteins Afra, Sumaiya Prospective detection methods for Tau protein: an important biomarker for Alzheimer’s disease |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. |
| author2 |
Yasmin, Hasina |
| author_facet |
Yasmin, Hasina Afra, Sumaiya |
| format |
Thesis |
| author |
Afra, Sumaiya |
| author_sort |
Afra, Sumaiya |
| title |
Prospective detection methods for Tau protein: an important biomarker for Alzheimer’s disease |
| title_short |
Prospective detection methods for Tau protein: an important biomarker for Alzheimer’s disease |
| title_full |
Prospective detection methods for Tau protein: an important biomarker for Alzheimer’s disease |
| title_fullStr |
Prospective detection methods for Tau protein: an important biomarker for Alzheimer’s disease |
| title_full_unstemmed |
Prospective detection methods for Tau protein: an important biomarker for Alzheimer’s disease |
| title_sort |
prospective detection methods for tau protein: an important biomarker for alzheimer’s disease |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/17191 |
| work_keys_str_mv |
AT afrasumaiya prospectivedetectionmethodsfortauproteinanimportantbiomarkerforalzheimersdisease |
| _version_ |
1814309131884953600 |