Comparison of HPLC metabolite profile and antioxidant activity of aqueous extract of Ginkgo Biloba from Two commercial products available in Bangladesh market
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020.
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Brac University
2022
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| 在线阅读: | http://hdl.handle.net/10361/17147 |
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10361-171472022-09-04T21:01:33Z Comparison of HPLC metabolite profile and antioxidant activity of aqueous extract of Ginkgo Biloba from Two commercial products available in Bangladesh market Ahmed, Sarin Akter, Dr. Raushanara Department of Pharmacy, Brac University Ginkgo biloba Antioxidant activity Metabolite profile DPPH TPC TFC Ginkgo--Therapeutic use. Metabolic profile tests--Laboratory manuals. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 72-79). The availability of several brands of Ginkgo biloba in Bangladesh market places the health professionals in a confused situation when selecting the desired quality product for patients. This study was aimed to evaluate the quality by comparing antioxidant activities and HPLC metabolite profile of two brands formulated from Ginkgo biloba, purchased from retail pharmacies. These drugs are widely used in blood disorders, COPD symptoms, Alzheimer’s disease, Raynaud’s disease, peripheral vascular disease. In DPPH free radical scavenging assay, the highest % of inhibition for sample 1 and 2 was 88.022% and 86.892%. At the highest concentration of 1200 µg/mL, sample 1 extract showed higher value in TPC, TFC and TAC test. In HPLC metabolite profile, quercetin and kaempferol amount for sample 1 was also better than sample 2. Based on the study findings, sample 1 is expected to produce more therapeutic effect than sample 2. Sarin Ahmed B. Pharmacy 2022-09-04T04:31:30Z 2022-09-04T04:31:30Z 2020 2020-02 Thesis ID: 15346038 http://hdl.handle.net/10361/17147 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 79 Pages application/pdf Brac University |
| institution |
Brac University |
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Institutional Repository |
| language |
en_US |
| topic |
Ginkgo biloba Antioxidant activity Metabolite profile DPPH TPC TFC Ginkgo--Therapeutic use. Metabolic profile tests--Laboratory manuals. |
| spellingShingle |
Ginkgo biloba Antioxidant activity Metabolite profile DPPH TPC TFC Ginkgo--Therapeutic use. Metabolic profile tests--Laboratory manuals. Ahmed, Sarin Comparison of HPLC metabolite profile and antioxidant activity of aqueous extract of Ginkgo Biloba from Two commercial products available in Bangladesh market |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. |
| author2 |
Akter, Dr. Raushanara |
| author_facet |
Akter, Dr. Raushanara Ahmed, Sarin |
| format |
Thesis |
| author |
Ahmed, Sarin |
| author_sort |
Ahmed, Sarin |
| title |
Comparison of HPLC metabolite profile and antioxidant activity of aqueous extract of Ginkgo Biloba from Two commercial products available in Bangladesh market |
| title_short |
Comparison of HPLC metabolite profile and antioxidant activity of aqueous extract of Ginkgo Biloba from Two commercial products available in Bangladesh market |
| title_full |
Comparison of HPLC metabolite profile and antioxidant activity of aqueous extract of Ginkgo Biloba from Two commercial products available in Bangladesh market |
| title_fullStr |
Comparison of HPLC metabolite profile and antioxidant activity of aqueous extract of Ginkgo Biloba from Two commercial products available in Bangladesh market |
| title_full_unstemmed |
Comparison of HPLC metabolite profile and antioxidant activity of aqueous extract of Ginkgo Biloba from Two commercial products available in Bangladesh market |
| title_sort |
comparison of hplc metabolite profile and antioxidant activity of aqueous extract of ginkgo biloba from two commercial products available in bangladesh market |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/17147 |
| work_keys_str_mv |
AT ahmedsarin comparisonofhplcmetaboliteprofileandantioxidantactivityofaqueousextractofginkgobilobafromtwocommercialproductsavailableinbangladeshmarket |
| _version_ |
1814306879586697216 |