Progress of edible vaccine development
This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2022.
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Brac University
2022
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10361-171132022-08-23T21:01:37Z Progress of edible vaccine development Razna, Amrin Islam Hossain, Mohammed Mahboob Department of Mathematics and Natural Sciences, Brac University Edible Vaccines Secretory IgA Antibodies Transformation GM1-ELISA Vaccines--Development Vaccines--Developing countries This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2022. Cataloged from PDF version of thesis. Includes bibliographical references (pages 89-103). Edible vaccines are edible plants genetically engineered to contain a gene that specifies an antigen or a marker sequence sequence of defective gene or protein. The mucous lining comprises one of the first lines of defense during pathogen attack and a vaccine usually triggers the mucosal immune system of the mucous lining. The dissertation will highlight the development framework of the edible vaccine, the timeframe of development along their proposed uses. The encapsulation of the antigen in the plant vehicles‘ tissues protects the antigen from the acidic nature of the stomach. The immunogen, being in partially intact form, would be able to stimulate an immune response. Edible vaccines could be further used to induce tolerance to allergens. For such cases, the immunogen is in soluble form. Studies have revealed that these vaccines can stimulate the production of secretory IgA along with other antibodies. Currently, six edible vaccines are undergoing clinical trials; however, certain issues need to be solved before their approval. Veterinary edible vaccines have been already approved. Bangladesh has also attempted to design an edible vaccine for pneumonia. It can be inferred that shortly, edible vaccines would be a valuable tool for preventing health conditions. Amrin Islam Razna M. Biotechnology 2022-08-23T04:10:38Z 2022-08-23T04:10:38Z 2022 2022-02 Thesis ID: 18276008 http://hdl.handle.net/10361/17113 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 103 Pages application/pdf Brac University |
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Brac University |
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Institutional Repository |
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en_US |
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Edible Vaccines Secretory IgA Antibodies Transformation GM1-ELISA Vaccines--Development Vaccines--Developing countries |
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Edible Vaccines Secretory IgA Antibodies Transformation GM1-ELISA Vaccines--Development Vaccines--Developing countries Razna, Amrin Islam Progress of edible vaccine development |
description |
This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2022. |
author2 |
Hossain, Mohammed Mahboob |
author_facet |
Hossain, Mohammed Mahboob Razna, Amrin Islam |
format |
Thesis |
author |
Razna, Amrin Islam |
author_sort |
Razna, Amrin Islam |
title |
Progress of edible vaccine development |
title_short |
Progress of edible vaccine development |
title_full |
Progress of edible vaccine development |
title_fullStr |
Progress of edible vaccine development |
title_full_unstemmed |
Progress of edible vaccine development |
title_sort |
progress of edible vaccine development |
publisher |
Brac University |
publishDate |
2022 |
url |
http://hdl.handle.net/10361/17113 |
work_keys_str_mv |
AT raznaamrinislam progressofediblevaccinedevelopment |
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