Phytochemical screening, antimicrobial and cytotoxicity studies of Heritiera fomes
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020.
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| स्वरूप: | थीसिस |
| भाषा: | English |
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Brac University
2022
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| ऑनलाइन पहुंच: | http://hdl.handle.net/10361/17031 |
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10361-170312022-07-25T21:01:33Z Phytochemical screening, antimicrobial and cytotoxicity studies of Heritiera fomes Tabassum, Rifah Ripa, Farhana Alam Department of Pharmacy, Brac University Heritiera fomes Phytochemical screening Brine shrimp lethality bioassay Antimicrobial activity Disk diffusion method This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 46-48). The present study was conducted to find out phytochemical constituents, cytotoxic property and antimicrobial effect of available parts of Heritiera fomes by using different solvents during extraction. The phytochemical screening was performed following Standard Method. Presence of cytotoxicity was tested by in-vitro brine shrimp lethality bioassay with different concentrations (400μg/mL-1200μg/mL). Antimicrobial activity was tested by disk diffusion method with concentrations of 500μg/mL and 1000μg/mL. Alkaloids, steroids, resins were some of the chemical constituents identified during phytochemical screening. The plant indicated antimicrobial activity in dose-dependent manner with highest effect against Shigella dysenteriae and Shigella boydii when Ethyl Acetate was present as solvent. The mortality rate due to cytotoxic effect was observed below 50% and maximum cytotoxicity level was found in root extracts. Although experimented extract showed antimicrobial effect presence of which responsible bioactive compounds behind it was not investigated, thus further work regarding this can be done. Rifah Tabassum B. Pharmacy 2022-07-25T03:48:26Z 2022-07-25T03:48:26Z 2020 2020-03 Thesis ID 16146029 http://hdl.handle.net/10361/17031 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 48 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Heritiera fomes Phytochemical screening Brine shrimp lethality bioassay Antimicrobial activity Disk diffusion method |
| spellingShingle |
Heritiera fomes Phytochemical screening Brine shrimp lethality bioassay Antimicrobial activity Disk diffusion method Tabassum, Rifah Phytochemical screening, antimicrobial and cytotoxicity studies of Heritiera fomes |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. |
| author2 |
Ripa, Farhana Alam |
| author_facet |
Ripa, Farhana Alam Tabassum, Rifah |
| format |
Thesis |
| author |
Tabassum, Rifah |
| author_sort |
Tabassum, Rifah |
| title |
Phytochemical screening, antimicrobial and cytotoxicity studies of Heritiera fomes |
| title_short |
Phytochemical screening, antimicrobial and cytotoxicity studies of Heritiera fomes |
| title_full |
Phytochemical screening, antimicrobial and cytotoxicity studies of Heritiera fomes |
| title_fullStr |
Phytochemical screening, antimicrobial and cytotoxicity studies of Heritiera fomes |
| title_full_unstemmed |
Phytochemical screening, antimicrobial and cytotoxicity studies of Heritiera fomes |
| title_sort |
phytochemical screening, antimicrobial and cytotoxicity studies of heritiera fomes |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/17031 |
| work_keys_str_mv |
AT tabassumrifah phytochemicalscreeningantimicrobialandcytotoxicitystudiesofheritierafomes |
| _version_ |
1814307804894199808 |