Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017
This article was published in The Lancet [ © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access Article under the CC BY 4.0 license..] and the definite version is available at: https://doi.org/10.1016/S0140-6736(20)30045-3. The Journal's website is at: https://www.thelancet.c...
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Lancet
2022
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| 在線閱讀: | http://hdl.handle.net/10361/16563 https://doi.org/10.1016/S0140-6736(20)30045-3 |
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10361-16563 |
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Brac University |
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en_US |
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Chronic kidney disease Global Burden of Disease Study 2017 |
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Chronic kidney disease Global Burden of Disease Study 2017 GBD Chronic Kidney Disease Collaboration Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017 |
| description |
This article was published in The Lancet [ © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access Article under the CC BY 4.0 license..] and the definite version is available at: https://doi.org/10.1016/S0140-6736(20)30045-3. The Journal's website is at: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30045-3/fulltext#%20 |
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Brac James P. Grant School of Public Health |
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Brac James P. Grant School of Public Health GBD Chronic Kidney Disease Collaboration |
| format |
Journal Article |
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GBD Chronic Kidney Disease Collaboration |
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GBD Chronic Kidney Disease Collaboration |
| title |
Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017 |
| title_short |
Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017 |
| title_full |
Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017 |
| title_fullStr |
Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017 |
| title_full_unstemmed |
Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017 |
| title_sort |
global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the global burden of disease study 2017 |
| publisher |
Lancet |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/16563 https://doi.org/10.1016/S0140-6736(20)30045-3 |
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10361-165632022-04-24T21:03:52Z Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017 GBD Chronic Kidney Disease Collaboration Brac James P. Grant School of Public Health Chronic kidney disease Global Burden of Disease Study 2017 This article was published in The Lancet [ © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access Article under the CC BY 4.0 license..] and the definite version is available at: https://doi.org/10.1016/S0140-6736(20)30045-3. The Journal's website is at: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30045-3/fulltext#%20 Background Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries. We estimated the global, regional, and national burden of CKD, as well as the burden of cardiovascular disease and gout attributable to impaired kidney function, for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. We use the term CKD to refer to the morbidity and mortality that can be directly attributed to all stages of CKD, and we use the term impaired kidney function to refer to the additional risk of CKD from cardiovascular disease and gout. Methods The main data sources we used were published literature, vital registration systems, end-stage kidney disease registries, and household surveys. Estimates of CKD burden were produced using a Cause of Death Ensemble model and a Bayesian meta-regression analytical tool, and included incidence, prevalence, years lived with disability, mortality, years of life lost, and disability-adjusted life-years (DALYs). A comparative risk assessment approach was used to estimate the proportion of cardiovascular diseases and gout burden attributable to impaired kidney function. Findings Globally, in 2017, 1·2 million (95% uncertainty interval [UI] 1·2 to 1·3) people died from CKD. The global all-age mortality rate from CKD increased 41·5% (95% UI 35·2 to 46·5) between 1990 and 2017, although there was no significant change in the age-standardised mortality rate (2·8%, –1·5 to 6·3). In 2017, 697·5 million (95% UI 649·2 to 752·0) cases of all-stage CKD were recorded, for a global prevalence of 9·1% (8·5 to 9·8). The global all-age prevalence of CKD increased 29·3% (95% UI 26·4 to 32·6) since 1990, whereas the age-standardised prevalence remained stable (1·2%, –1·1 to 3·5). CKD resulted in 35·8 million (95% UI 33·7 to 38·0) DALYs in 2017, with diabetic nephropathy accounting for almost a third of DALYs. Most of the burden of CKD was concentrated in the three lowest quintiles of Socio-demographic Index (SDI). In several regions, particularly Oceania, sub-Saharan Africa, and Latin America, the burden of CKD was much higher than expected for the level of development, whereas the disease burden in western, eastern, and central sub-Saharan Africa, east Asia, south Asia, central and eastern Europe, Australasia, and western Europe was lower than expected. 1·4 million (95% UI 1·2 to 1·6) cardiovascular diseaserelated deaths and 25·3 million (22·2 to 28·9) cardiovascular disease DALYs were attributable to impaired kidney function. Interpretation Kidney disease has a major effect on global health, both as a direct cause of global morbidity and mortality and as an important risk factor for cardiovascular disease. CKD is largely preventable and treatable and deserves greater attention in global health policy decision making, particularly in locations with low and middle SDI. Published 2022-04-24T06:56:23Z 2022-04-24T06:56:23Z 2020 2020-02-13 Journal Article Bikbov, B., Purcell, C. A., Levey, A. S., Smith, M., Abdoli, A., Abebe, M., . . . Murray, C. J. L. (2020). Global, regional, and national burden of chronic kidney disease, 1990–2017: A systematic analysis for the global burden of disease study 2017. The Lancet, 395(10225), 709-733. doi:10.1016/S0140-6736(20)30045-3 http://hdl.handle.net/10361/16563 https://doi.org/10.1016/S0140-6736(20)30045-3 en_US https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30045-3/fulltext#%20 application/pdf Lancet |