A review on the role of Myc and miRNA in Glioblastoma multiforme
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020.
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Brac University
2022
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10361-165322022-04-11T21:01:35Z A review on the role of Myc and miRNA in Glioblastoma multiforme Naureen, Ishrat Akter, Raushanara Department of Pharmacy, Brac University C-Myc miRNA Therapeutic target Malignant Glioblastoma multiforme (GBM) Glioblastoma multiforme. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 50-58). Glioblastoma multiforme (GBM) is known as one of the most belligerent and malignant brain tumors in adults. Among the four grades of brain cancers, the glioblastoma is considered as the most infiltrative one. GBMs account for 60%–70% of malignant glioma. The median survival period of patients with such types of cancers usually exceeds from one year to fifteen months after treatment. Scientists are now approaching toward alternative ways of treating glioblastoma permanently. Different types of microRNA (miRNA) and the Myc oncogene play a vital role in regulation of multiple downstream targets to bring about alterations in gene mutation, chromosomal stability and inflection of tumor growth. This review paper delineates the role of Myc and microRNA in metabolism of glucose and tumor growth. Along with the possible utilization of C-Myc and miRNA, and how C-Myc and miRNA can perform the role of biomarkers and therapeutic targets for glioblastoma multiforme. Ishrat Naureen B. Pharmacy 2022-04-11T04:09:09Z 2022-04-11T04:09:09Z 2020 2020-01 Thesis ID 13346024 http://hdl.handle.net/10361/16532 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 58 pages application/pdf Brac University |
institution |
Brac University |
collection |
Institutional Repository |
language |
English |
topic |
C-Myc miRNA Therapeutic target Malignant Glioblastoma multiforme (GBM) Glioblastoma multiforme. |
spellingShingle |
C-Myc miRNA Therapeutic target Malignant Glioblastoma multiforme (GBM) Glioblastoma multiforme. Naureen, Ishrat A review on the role of Myc and miRNA in Glioblastoma multiforme |
description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. |
author2 |
Akter, Raushanara |
author_facet |
Akter, Raushanara Naureen, Ishrat |
format |
Thesis |
author |
Naureen, Ishrat |
author_sort |
Naureen, Ishrat |
title |
A review on the role of Myc and miRNA in Glioblastoma multiforme |
title_short |
A review on the role of Myc and miRNA in Glioblastoma multiforme |
title_full |
A review on the role of Myc and miRNA in Glioblastoma multiforme |
title_fullStr |
A review on the role of Myc and miRNA in Glioblastoma multiforme |
title_full_unstemmed |
A review on the role of Myc and miRNA in Glioblastoma multiforme |
title_sort |
review on the role of myc and mirna in glioblastoma multiforme |
publisher |
Brac University |
publishDate |
2022 |
url |
http://hdl.handle.net/10361/16532 |
work_keys_str_mv |
AT naureenishrat areviewontheroleofmycandmirnainglioblastomamultiforme AT naureenishrat reviewontheroleofmycandmirnainglioblastomamultiforme |
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