A study of Osteosarcoma gene profile
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021.
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Brac University
2022
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| 在线阅读: | http://hdl.handle.net/10361/15956 |
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10361-159562022-01-19T21:01:25Z A study of Osteosarcoma gene profile Arka, Sadib Md. Jamiruddin, Mohd. Raeed Department of Pharmacy, Brac University Microarray analysis Gene expression R software Heatmap Bone cancer Osteosarcoma Oncology This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 24-32). Osteosarcoma is a type of bone cancer casting huge threat to the human health worldwide. It is a primary bone malignancy with a particularly high incidence rate in children and adolescents relative to other age groups. The etiology of this often aggressive cancer is currently unknown, because complicated structural and numeric genomic rearrangements in cancer cells preclude understanding of tumour development. The aim of the study is to analyze gene expression to identify biomarkers for osteosarcoma. We downloaded and mined two expression profile datasets associated with osteosarcoma from the Gene Expression Omnibus. After data background correction we analyzed the data using R studio software. However, we could not achieve our cherished result due to some package error in the software. Though we could not figure out the possible biomarkers using our data but some studies has been found that gene which take part in antigen presentation and immune process are highly expressed in the escalation of osteosarcoma cell growth the expression genes in all were shown as heatmap. Doing further study of osteosarcoma cell growth, it may help to facilitate the individual management of patients with osteosarcoma after treatment. Sadib Md. Arka B. Pharmacy 2022-01-19T05:10:09Z 2022-01-19T05:10:09Z 2020 2020-01 Thesis ID 15146005 http://hdl.handle.net/10361/15956 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 32 pages application/pdf Brac University |
| institution |
Brac University |
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Institutional Repository |
| language |
English |
| topic |
Microarray analysis Gene expression R software Heatmap Bone cancer Osteosarcoma Oncology |
| spellingShingle |
Microarray analysis Gene expression R software Heatmap Bone cancer Osteosarcoma Oncology Arka, Sadib Md. A study of Osteosarcoma gene profile |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. |
| author2 |
Jamiruddin, Mohd. Raeed |
| author_facet |
Jamiruddin, Mohd. Raeed Arka, Sadib Md. |
| format |
Thesis |
| author |
Arka, Sadib Md. |
| author_sort |
Arka, Sadib Md. |
| title |
A study of Osteosarcoma gene profile |
| title_short |
A study of Osteosarcoma gene profile |
| title_full |
A study of Osteosarcoma gene profile |
| title_fullStr |
A study of Osteosarcoma gene profile |
| title_full_unstemmed |
A study of Osteosarcoma gene profile |
| title_sort |
study of osteosarcoma gene profile |
| publisher |
Brac University |
| publishDate |
2022 |
| url |
http://hdl.handle.net/10361/15956 |
| work_keys_str_mv |
AT arkasadibmd astudyofosteosarcomageneprofile AT arkasadibmd studyofosteosarcomageneprofile |
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