Comparative analysis reveals the contribution of phage-derived genomic islands to the increasing pathogenicity of facultative bacterial pathogens
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2020.
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| التنسيق: | أطروحة |
| اللغة: | English |
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Brac University
2021
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| الوصول للمادة أونلاين: | http://hdl.handle.net/10361/15558 |
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10361-15558 |
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10361-155582021-10-27T21:01:23Z Comparative analysis reveals the contribution of phage-derived genomic islands to the increasing pathogenicity of facultative bacterial pathogens Poly, Israt Jahan Khan Naser, Iftekhar Bin Tareq, Tokee Mohammad Department of Mathematics and Natural Sciences, Brac University Bacterial pathogenicity Phage derived genomic islands Virulence factors Pathogenic bacteria. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2020. Catalogued from PDF version of thesis. Includes bibliographical references (pages 34-42). Bacteriophages are the most abundant entity in the biosphere outnumbering bacteria by a factor of at least 10. Other than infecting bacteria, phages also influence the evolution of bacteria in an unexpected way to provide more pathogenicity to the species in the course of time. It has thereby become very significant to establish an equation between bacterial increased pathogenicity and phage derived genome islands. Computational analysis of vast number of bacterial pathogenic genomes divided by two different time periods (before and after 1990) yielded the virulence regions emerging from prophages. Notable addition of pathogenic phage proteins was observed in bacteria of the latter time periods indicating increase in the pathogenesis of already pathogenic bacteria. As we have few information on phage diversity and their contribution on bacterial evolution, hence this study would create an opportunity to understand their relationship to a great extent. Israt Jahan Khan Poly B. Biotechnology 2021-10-27T05:05:32Z 2021-10-27T05:05:32Z 2020 2020-09 Thesis ID 16136009 http://hdl.handle.net/10361/15558 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 42 pages application/pdf Brac University |
| institution |
Brac University |
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Institutional Repository |
| language |
English |
| topic |
Bacterial pathogenicity Phage derived genomic islands Virulence factors Pathogenic bacteria. |
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Bacterial pathogenicity Phage derived genomic islands Virulence factors Pathogenic bacteria. Poly, Israt Jahan Khan Comparative analysis reveals the contribution of phage-derived genomic islands to the increasing pathogenicity of facultative bacterial pathogens |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2020. |
| author2 |
Naser, Iftekhar Bin |
| author_facet |
Naser, Iftekhar Bin Poly, Israt Jahan Khan |
| format |
Thesis |
| author |
Poly, Israt Jahan Khan |
| author_sort |
Poly, Israt Jahan Khan |
| title |
Comparative analysis reveals the contribution of phage-derived genomic islands to the increasing pathogenicity of facultative bacterial pathogens |
| title_short |
Comparative analysis reveals the contribution of phage-derived genomic islands to the increasing pathogenicity of facultative bacterial pathogens |
| title_full |
Comparative analysis reveals the contribution of phage-derived genomic islands to the increasing pathogenicity of facultative bacterial pathogens |
| title_fullStr |
Comparative analysis reveals the contribution of phage-derived genomic islands to the increasing pathogenicity of facultative bacterial pathogens |
| title_full_unstemmed |
Comparative analysis reveals the contribution of phage-derived genomic islands to the increasing pathogenicity of facultative bacterial pathogens |
| title_sort |
comparative analysis reveals the contribution of phage-derived genomic islands to the increasing pathogenicity of facultative bacterial pathogens |
| publisher |
Brac University |
| publishDate |
2021 |
| url |
http://hdl.handle.net/10361/15558 |
| work_keys_str_mv |
AT polyisratjahankhan comparativeanalysisrevealsthecontributionofphagederivedgenomicislandstotheincreasingpathogenicityoffacultativebacterialpathogens |
| _version_ |
1814308967787003904 |