A review on insulin-producing beta cell: regenerative role of drugs acting on DYRK1A, GLP-1 and DPP-4 receptors
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021.
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| বিন্যাস: | গবেষণাপত্র |
| ভাষা: | English |
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Brac University
2021
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| অনলাইন ব্যবহার করুন: | http://hdl.handle.net/10361/15532 |
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10361-155322021-10-25T21:01:25Z A review on insulin-producing beta cell: regenerative role of drugs acting on DYRK1A, GLP-1 and DPP-4 receptors Mahmood, Nyrit Tahsin, Faria Department of Pharmacy, Brac University Dipeptidyl peptidase-4 Dual specificity tyrosine-phosphorylation-regulated kinase 1A Beta-cell regeneration Diabetes Glucagon-like peptide 1 Diabetes--Oral therapy This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 35-41). Approximately 422 million people have diabetes all over the world. The regeneration of the beta cell has been investigated for a longer time by scientists with the hope of newer potential opportunities, thus contributing to the treatment of diabetes. Beta-cell regeneration is a mechanism of producing new beta cells in the pancreas, which is responsible for the secretion of insulin, currently on pre-clinical trials. In this study, the action of each three receptors – GLP-1, DPP-4, and DYRK1A has been discussed. Their possibility of combination in the regeneration of damaged beta cells for the welfare of diabetic patients by comparing the ability of each of the receptors to regenerate beta cells as well as the combination of actions on these receptors produce any better effect or not has also been analyzed. However, millions of people with diabetes have a ray of hope as the current use of GLP-1 and DYRK1A indicates a prospective technique based on DYRK1A inhibition with the GLP-1 receptor. Moreover, it is also a fact that still there is no evidence of any potential combined treatment with the use of GLP-1 and DPP-4 for diabetic patients. Nyrit Mahmood B. Pharmacy 2021-10-25T05:31:51Z 2021-10-25T05:31:51Z 2021 2021-05 Thesis ID 17146013 http://hdl.handle.net/10361/15532 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 41 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Dipeptidyl peptidase-4 Dual specificity tyrosine-phosphorylation-regulated kinase 1A Beta-cell regeneration Diabetes Glucagon-like peptide 1 Diabetes--Oral therapy |
| spellingShingle |
Dipeptidyl peptidase-4 Dual specificity tyrosine-phosphorylation-regulated kinase 1A Beta-cell regeneration Diabetes Glucagon-like peptide 1 Diabetes--Oral therapy Mahmood, Nyrit A review on insulin-producing beta cell: regenerative role of drugs acting on DYRK1A, GLP-1 and DPP-4 receptors |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. |
| author2 |
Tahsin, Faria |
| author_facet |
Tahsin, Faria Mahmood, Nyrit |
| format |
Thesis |
| author |
Mahmood, Nyrit |
| author_sort |
Mahmood, Nyrit |
| title |
A review on insulin-producing beta cell: regenerative role of drugs acting on DYRK1A, GLP-1 and DPP-4 receptors |
| title_short |
A review on insulin-producing beta cell: regenerative role of drugs acting on DYRK1A, GLP-1 and DPP-4 receptors |
| title_full |
A review on insulin-producing beta cell: regenerative role of drugs acting on DYRK1A, GLP-1 and DPP-4 receptors |
| title_fullStr |
A review on insulin-producing beta cell: regenerative role of drugs acting on DYRK1A, GLP-1 and DPP-4 receptors |
| title_full_unstemmed |
A review on insulin-producing beta cell: regenerative role of drugs acting on DYRK1A, GLP-1 and DPP-4 receptors |
| title_sort |
review on insulin-producing beta cell: regenerative role of drugs acting on dyrk1a, glp-1 and dpp-4 receptors |
| publisher |
Brac University |
| publishDate |
2021 |
| url |
http://hdl.handle.net/10361/15532 |
| work_keys_str_mv |
AT mahmoodnyrit areviewoninsulinproducingbetacellregenerativeroleofdrugsactingondyrk1aglp1anddpp4receptors AT mahmoodnyrit reviewoninsulinproducingbetacellregenerativeroleofdrugsactingondyrk1aglp1anddpp4receptors |
| _version_ |
1814307131716796416 |