Potential use of Vibriophage in association with antibiotic to treat the vibrio Cholerae biofilm
This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2021.
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| Lenguaje: | English |
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Brac University
2021
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| Acceso en línea: | http://hdl.handle.net/10361/15211 |
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10361-15211 |
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10361-152112021-10-11T21:01:28Z Potential use of Vibriophage in association with antibiotic to treat the vibrio Cholerae biofilm Farheen, Saria Naser, Iftekhar Bin Department of Mathematics and Natural Sciences, Brac University Bacteriophage V.cholerae Biofilm Antibiotic Bacterial genetics Bacteriophages--Genetics This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2021. Catalogued from PDF version of thesis. Includes bibliographical references (pages 45-57). In cholera prevalent areas, Vibrio cholerae in the aqueous environment can exist in a cell aggregated form covered by an extra polysaccharide matrix called Biofilm. These type of cells are named as VBNC (viable but non culturable cell) and CVEC (conditionally viable environmental cell). The cells in the biofilm can persist in a wide range of environmental conditions by remaining metabolically dormant and can resuscitate into planktonic cells leading to a cholera outbreak. So it is imperative to treat these biofilms. It has been found that antibiotic treatment is not effective in degrading the biofilm and also can lead to the dissemination of antibiotic resistance genes. So as a safe alternative, this study has shown the use of a bacteriophage to degrade the pathogenic V. cholerae biofilm. This study also shows the synergistic effect of antibiotics and bacteriophages on the elimination of toxigenic Vibrio biofilms. Saria Farheen M. Biotechnology 2021-10-11T07:06:05Z 2021-10-11T07:06:05Z 2021 2021-08 Thesis ID 19176003 http://hdl.handle.net/10361/15211 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 58 pages application/pdf Brac University |
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Brac University |
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Institutional Repository |
| language |
English |
| topic |
Bacteriophage V.cholerae Biofilm Antibiotic Bacterial genetics Bacteriophages--Genetics |
| spellingShingle |
Bacteriophage V.cholerae Biofilm Antibiotic Bacterial genetics Bacteriophages--Genetics Farheen, Saria Potential use of Vibriophage in association with antibiotic to treat the vibrio Cholerae biofilm |
| description |
This thesis report is submitted in partial fulfillment of the requirement for the degree of Master of Science in Biotechnology, 2021. |
| author2 |
Naser, Iftekhar Bin |
| author_facet |
Naser, Iftekhar Bin Farheen, Saria |
| format |
Thesis |
| author |
Farheen, Saria |
| author_sort |
Farheen, Saria |
| title |
Potential use of Vibriophage in association with antibiotic to treat the vibrio Cholerae biofilm |
| title_short |
Potential use of Vibriophage in association with antibiotic to treat the vibrio Cholerae biofilm |
| title_full |
Potential use of Vibriophage in association with antibiotic to treat the vibrio Cholerae biofilm |
| title_fullStr |
Potential use of Vibriophage in association with antibiotic to treat the vibrio Cholerae biofilm |
| title_full_unstemmed |
Potential use of Vibriophage in association with antibiotic to treat the vibrio Cholerae biofilm |
| title_sort |
potential use of vibriophage in association with antibiotic to treat the vibrio cholerae biofilm |
| publisher |
Brac University |
| publishDate |
2021 |
| url |
http://hdl.handle.net/10361/15211 |
| work_keys_str_mv |
AT farheensaria potentialuseofvibriophageinassociationwithantibiotictotreatthevibriocholeraebiofilm |
| _version_ |
1814309707665375232 |