Effect of SIRT6 on smooth muscle tissues and Epithelial Tissues- A Review
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021.
| 1. autor: | |
|---|---|
| Kolejni autorzy: | |
| Format: | Praca dyplomowa |
| Język: | en_US |
| Wydane: |
BRAC University
2021
|
| Hasła przedmiotowe: | |
| Dostęp online: | http://hdl.handle.net/10361/15068 |
| id |
10361-15068 |
|---|---|
| record_format |
dspace |
| spelling |
10361-150682021-09-29T21:01:31Z Effect of SIRT6 on smooth muscle tissues and Epithelial Tissues- A Review Roy, Puja Akter, Raushanara Department of Pharmacy, Brac University Sirtuin 6 Disease Smooth Muscle Tissues Epithelial Tissues Therapeutic Targe This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 41-50). SIRT6 is a stress response protein belongs to sirtuin family. It is involved in different multiple molecular pathways that are linked to DNA repair, neurodegeneration, tumorigenesis, glycolysis, gluconeogenesis, cardiac hypertrophy, metabolism etc. The up-regulation and down-regulation of this histone deacetylase involve in different diseases such as Alzheimer’s disease, aging, cancer, inflammation, diabetes, and cardiac problems. Thus, it has emerged as an important therapeutic target for the mentioned diseases. This review aims to compile available information regarding SIRT6 and its effect on smooth muscle- and epithelial tissues for predicting future target therapeutic approach. This review information exhibited that increased SIRT6 activity helps to combat diabetic atherosclerotic plaque; heal wound; inhibit EMT; save from pulmonary, cardiac, biliary and renal cell injury; decrease metabolic disease; glioma cell proliferation whereas decreased SIRT6 activity may improve Parkinson’s disease. Therapeutic approach can be developed by looking these sorts of effects of SIRT6 in cellular and molecular level. Puja Roy B. Pharmacy 2021-09-29T03:29:14Z 2021-09-29T03:29:14Z 2021 2021-02 Thesis ID: 16346039 http://hdl.handle.net/10361/15068 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 50 Pages application/pdf BRAC University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
en_US |
| topic |
Sirtuin 6 Disease Smooth Muscle Tissues Epithelial Tissues Therapeutic Targe |
| spellingShingle |
Sirtuin 6 Disease Smooth Muscle Tissues Epithelial Tissues Therapeutic Targe Roy, Puja Effect of SIRT6 on smooth muscle tissues and Epithelial Tissues- A Review |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. |
| author2 |
Akter, Raushanara |
| author_facet |
Akter, Raushanara Roy, Puja |
| format |
Thesis |
| author |
Roy, Puja |
| author_sort |
Roy, Puja |
| title |
Effect of SIRT6 on smooth muscle tissues and Epithelial Tissues- A Review |
| title_short |
Effect of SIRT6 on smooth muscle tissues and Epithelial Tissues- A Review |
| title_full |
Effect of SIRT6 on smooth muscle tissues and Epithelial Tissues- A Review |
| title_fullStr |
Effect of SIRT6 on smooth muscle tissues and Epithelial Tissues- A Review |
| title_full_unstemmed |
Effect of SIRT6 on smooth muscle tissues and Epithelial Tissues- A Review |
| title_sort |
effect of sirt6 on smooth muscle tissues and epithelial tissues- a review |
| publisher |
BRAC University |
| publishDate |
2021 |
| url |
http://hdl.handle.net/10361/15068 |
| work_keys_str_mv |
AT roypuja effectofsirt6onsmoothmuscletissuesandepithelialtissuesareview |
| _version_ |
1814309121816526848 |