Isolation of bacteriophage with antimicrobial activity against Shigella Dysenteriae from sewage sample
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2019.
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BRAC University
2021
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| Acesso em linha: | http://hdl.handle.net/10361/15067 |
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10361-150672021-09-29T21:01:29Z Isolation of bacteriophage with antimicrobial activity against Shigella Dysenteriae from sewage sample Fahad, Dewan Al Mustafiz, Tasmia Binta Haque, Fahim Kabir Monjurul Department of Mathematics and Natural Sciences, Brac University Phage isolation Shigella dysenteriae Phage therapy This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2019. Catalogued from PDF version of thesis. Includes bibliographical references (pages 22-23). Shigellosis infection, caused by a genus of medically important bacteria called Shigella, results in diarrhea and other painful manifestations in humans. Annually, an estimated 74,000 to 600,000 people die of Shigella infection worldwide. Among the most lethal species of Shigella is Shigella dysenteriae, which produces the Shiga toxin upon infection. As a treatment, several antibiotics are prescribed to the patients suffering from shigellosis. However, recent studies have shown Shigella dysenteriae, along with several other species of bacteria, to have developed resistance against the common antibiotics; and, many of them were multidrug-resistant. In order to counter this problem, widespread research is ongoing in attempts to develop treatments of Shigellosis alternative to antibiotics intake, including phage therapy. Phage therapy is the therapeutic use of bacteriophages in treating bacterial infections. The initial step in the long process of developing successful phage therapy against a particular pathogenic infection is the isolation of phage(s) from the environment. In this study, we have isolated bacteriophages from hospital sewage and confirmed the phages’ antimicrobial activity against ATCC strains of Shigella dysenteriae. Dewan Al Fahad Tasmia Binta Mustafiz B. Biotechnology 2021-09-29T03:20:04Z 2021-09-29T03:20:04Z 2019 2019-10 Thesis ID: 15336005 ID: 15336016 http://hdl.handle.net/10361/15067 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 23 Pages application/pdf BRAC University |
| institution |
Brac University |
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Institutional Repository |
| language |
en_US |
| topic |
Phage isolation Shigella dysenteriae Phage therapy |
| spellingShingle |
Phage isolation Shigella dysenteriae Phage therapy Fahad, Dewan Al Mustafiz, Tasmia Binta Isolation of bacteriophage with antimicrobial activity against Shigella Dysenteriae from sewage sample |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2019. |
| author2 |
Haque, Fahim Kabir Monjurul |
| author_facet |
Haque, Fahim Kabir Monjurul Fahad, Dewan Al Mustafiz, Tasmia Binta |
| format |
Thesis |
| author |
Fahad, Dewan Al Mustafiz, Tasmia Binta |
| author_sort |
Fahad, Dewan Al |
| title |
Isolation of bacteriophage with antimicrobial activity against Shigella Dysenteriae from sewage sample |
| title_short |
Isolation of bacteriophage with antimicrobial activity against Shigella Dysenteriae from sewage sample |
| title_full |
Isolation of bacteriophage with antimicrobial activity against Shigella Dysenteriae from sewage sample |
| title_fullStr |
Isolation of bacteriophage with antimicrobial activity against Shigella Dysenteriae from sewage sample |
| title_full_unstemmed |
Isolation of bacteriophage with antimicrobial activity against Shigella Dysenteriae from sewage sample |
| title_sort |
isolation of bacteriophage with antimicrobial activity against shigella dysenteriae from sewage sample |
| publisher |
BRAC University |
| publishDate |
2021 |
| url |
http://hdl.handle.net/10361/15067 |
| work_keys_str_mv |
AT fahaddewanal isolationofbacteriophagewithantimicrobialactivityagainstshigelladysenteriaefromsewagesample AT mustafiztasmiabinta isolationofbacteriophagewithantimicrobialactivityagainstshigelladysenteriaefromsewagesample |
| _version_ |
1814309427922075648 |