Implication of chronic stress and Diabetes in Cerebrovascular Dysfunction: A review study
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021.
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Brac University
2021
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10361-150072021-09-14T21:01:32Z Implication of chronic stress and Diabetes in Cerebrovascular Dysfunction: A review study Mayesha, Iffat Islam Kabir, Eva Rahman Siam, Mohammad Kawsar Sharif Department of Pharmacy, Brac University Cerebrovascular Dysfunction Chronic Stress Diabetes Oxidative Stress Reactive Oxygen Species Redox Balance Gene Regulatory Network Analysis This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 31-42). The aim of the review was to explore the effects of chronic stress and diabetes in cerebrovascular dysfunction and neurological disorder. The evidence of involvement of hyperglycaemia induced oxidative stress was found to be prominent to cause complications like vascular inflammation, and neurovascular impairments. The active participation of different chemokine, transcription factors and biochemical pathways/mechanisms were studied to breakdown the cross-talk between diabetes and cerebrovascular dysfunction. Thus, the main objective of this review is to explain the significant relationship between diabetes and cerebrovascular dysfunction by explaining the various biochemical pathways. This will be an aid to identify the role of oxidative, reactive oxygen species and genetic errors in progression of various co-morbidities. A better understanding of the correlation of chronic stress and diabetes may suggest alternate approaches to the treatment of neurological disorders through pharmaceutical interventions. Furthermore, studying the process by which oxidative stress affects the cerebro-vasculature and blood-brain barrier are essential for evaluating antioxidant therapies. Iffat Islam Mayesha B. Pharmacy 2021-09-14T06:47:45Z 2021-09-14T06:47:45Z 2021 2021-04 Thesis ID: 16346046 http://hdl.handle.net/10361/15007 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 42 Pages application/pdf Brac University |
| institution |
Brac University |
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Institutional Repository |
| language |
en_US |
| topic |
Cerebrovascular Dysfunction Chronic Stress Diabetes Oxidative Stress Reactive Oxygen Species Redox Balance Gene Regulatory Network Analysis |
| spellingShingle |
Cerebrovascular Dysfunction Chronic Stress Diabetes Oxidative Stress Reactive Oxygen Species Redox Balance Gene Regulatory Network Analysis Mayesha, Iffat Islam Implication of chronic stress and Diabetes in Cerebrovascular Dysfunction: A review study |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2021. |
| author2 |
Kabir, Eva Rahman |
| author_facet |
Kabir, Eva Rahman Mayesha, Iffat Islam |
| format |
Thesis |
| author |
Mayesha, Iffat Islam |
| author_sort |
Mayesha, Iffat Islam |
| title |
Implication of chronic stress and Diabetes in Cerebrovascular Dysfunction: A review study |
| title_short |
Implication of chronic stress and Diabetes in Cerebrovascular Dysfunction: A review study |
| title_full |
Implication of chronic stress and Diabetes in Cerebrovascular Dysfunction: A review study |
| title_fullStr |
Implication of chronic stress and Diabetes in Cerebrovascular Dysfunction: A review study |
| title_full_unstemmed |
Implication of chronic stress and Diabetes in Cerebrovascular Dysfunction: A review study |
| title_sort |
implication of chronic stress and diabetes in cerebrovascular dysfunction: a review study |
| publisher |
Brac University |
| publishDate |
2021 |
| url |
http://hdl.handle.net/10361/15007 |
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AT mayeshaiffatislam implicationofchronicstressanddiabetesincerebrovasculardysfunctionareviewstudy |
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