Prospects of Heart tissue Bioprinting for COVID-19 recovered patients with irreversible heart damage.
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2021.
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Brac University
2021
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10361-149982021-09-13T21:01:21Z Prospects of Heart tissue Bioprinting for COVID-19 recovered patients with irreversible heart damage. Akter, Fariya Naser, Iftekhar Bin Promon, Salman Khan Department of Mathematics and Natural Sciences, Brac University COVID-19 Irreversible heart tissue damage Regenerative medicine 3D Bioprinting This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2021. Catalogued from PDF version of thesis. Includes bibliographical references (pages 44-62). Endomyocardial biopsy of COVID-19 patients myocardium proves the presence of viral particles along with the cardiogenic shock. 78 out of 100 recovered individuals who take 71 days of treatment had cardiovascular involvement despite recovering from COVID-19. 76% of them had high sensitivity troponin which is an indicator of myocardial damage and 60% had myocardial inflammation, edema, and/or diffuse myocardial fibrosis. Besides, the recently recovered patient’s report reflects ventricular ejection fraction. Due to multiple mutations of the causative agent SARS-CoV-2, it’s still a mystery how we can defeat the virus. Numerous complications are associated with COVID-19 and studies found the association of cardiovascular complications in every individual despite the age consideration, recently. Cardiovascular complications are responsible for sudden cardiac death of both the infected and recovered COVID-19 patients along with long-term cardiovascular effects as damaged myocardial tissues are unable to regenerate and few portions of damaged myocardium can induce damage to the whole heart. The purpose of this research is to do a competitive analysis of the conventional tissue engineering techniques with the upgraded alternative 3D bioprinting to replace the damaged portion of the human heart due to COVID-19. Additionally, this study focuses on the key points for the regeneration of a functional, biocompatible heart that mimics the native heart and the potential of 3D bioprinting to be a novel alternative. Finally, the limitations and current challenges of these techniques are briefly discussed. Fariya Akter B. Biotechnology 2021-09-13T06:48:19Z 2021-09-13T06:48:19Z 2021 2021-05 Thesis ID: 17136019 http://hdl.handle.net/10361/14998 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 62 Pages application/pdf Brac University |
| institution |
Brac University |
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Institutional Repository |
| language |
en_US |
| topic |
COVID-19 Irreversible heart tissue damage Regenerative medicine 3D Bioprinting |
| spellingShingle |
COVID-19 Irreversible heart tissue damage Regenerative medicine 3D Bioprinting Akter, Fariya Prospects of Heart tissue Bioprinting for COVID-19 recovered patients with irreversible heart damage. |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Biotechnology 2021. |
| author2 |
Naser, Iftekhar Bin |
| author_facet |
Naser, Iftekhar Bin Akter, Fariya |
| format |
Thesis |
| author |
Akter, Fariya |
| author_sort |
Akter, Fariya |
| title |
Prospects of Heart tissue Bioprinting for COVID-19 recovered patients with irreversible heart damage. |
| title_short |
Prospects of Heart tissue Bioprinting for COVID-19 recovered patients with irreversible heart damage. |
| title_full |
Prospects of Heart tissue Bioprinting for COVID-19 recovered patients with irreversible heart damage. |
| title_fullStr |
Prospects of Heart tissue Bioprinting for COVID-19 recovered patients with irreversible heart damage. |
| title_full_unstemmed |
Prospects of Heart tissue Bioprinting for COVID-19 recovered patients with irreversible heart damage. |
| title_sort |
prospects of heart tissue bioprinting for covid-19 recovered patients with irreversible heart damage. |
| publisher |
Brac University |
| publishDate |
2021 |
| url |
http://hdl.handle.net/10361/14998 |
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AT akterfariya prospectsofhearttissuebioprintingforcovid19recoveredpatientswithirreversibleheartdamage |
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