Investigation of in-vitro biological potential of Methanol extract of Magnolia alba Leaves

This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020.

Chi tiết về thư mục
Tác giả chính: Sarah, Sabrina Hossain
Tác giả khác: Sharmin, Shahana
Định dạng: Luận văn
Ngôn ngữ:English
Được phát hành: Brac University 2021
Những chủ đề:
Truy cập trực tuyến:http://hdl.handle.net/10361/14947
id 10361-14947
record_format dspace
spelling 10361-149472021-08-04T21:01:28Z Investigation of in-vitro biological potential of Methanol extract of Magnolia alba Leaves Sarah, Sabrina Hossain Sharmin, Shahana Department of Pharmacy, Brac University Antioxidant Cytotoxicity Antimicrobial Magnolia alba Traditional medicine Medicinal plants Pharmacy This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 37-39). From immemorial time medicinal plants are used as an important source of medication for ailments and diseases. Now a day it has expanded the source of income also. In this experiment some pharmacological activities were screened from methanol extracted Magnolia alba leaf. Antioxidant properties were identified using DPPH assay. The data from this assay proved the existence of Antioxidant in this plan. Although the IC50 level of experimental plant leaves is comparatively lower than the standard (Ascorbic Acid). Later on, thrombolytic activity also tested, by it demonstrated 19.1% clot lysis which is lower than compared with the standard clopidogrel. Furthermore, evaluation of Cytotoxicity property done by Brine Shrimp Lethality Assay (BLSA). The result showed for Magnolia alba leaves was 7.904% whereas the standard vincristine sulphate showed 3.324%.It has appeared a higher level of cytotoxicity in this experimental plant but the antimicrobial test did not give any significant result though. Exploring new possibilities and expectations is the beauty of research. It seems this study will help to design future researches and discovering a new source of antioxidant, cardiovascular and anticancer drug with more effectiveness and safety. Sabrina Hossain Sarah B. Pharmacy 2021-08-04T17:42:24Z 2021-08-04T17:42:24Z 2020 2020-02 Thesis ID 15146030 http://hdl.handle.net/10361/14947 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 39 pages application/pdf Brac University
institution Brac University
collection Institutional Repository
language English
topic Antioxidant
Cytotoxicity
Antimicrobial
Magnolia alba
Traditional medicine
Medicinal plants
Pharmacy
spellingShingle Antioxidant
Cytotoxicity
Antimicrobial
Magnolia alba
Traditional medicine
Medicinal plants
Pharmacy
Sarah, Sabrina Hossain
Investigation of in-vitro biological potential of Methanol extract of Magnolia alba Leaves
description This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020.
author2 Sharmin, Shahana
author_facet Sharmin, Shahana
Sarah, Sabrina Hossain
format Thesis
author Sarah, Sabrina Hossain
author_sort Sarah, Sabrina Hossain
title Investigation of in-vitro biological potential of Methanol extract of Magnolia alba Leaves
title_short Investigation of in-vitro biological potential of Methanol extract of Magnolia alba Leaves
title_full Investigation of in-vitro biological potential of Methanol extract of Magnolia alba Leaves
title_fullStr Investigation of in-vitro biological potential of Methanol extract of Magnolia alba Leaves
title_full_unstemmed Investigation of in-vitro biological potential of Methanol extract of Magnolia alba Leaves
title_sort investigation of in-vitro biological potential of methanol extract of magnolia alba leaves
publisher Brac University
publishDate 2021
url http://hdl.handle.net/10361/14947
work_keys_str_mv AT sarahsabrinahossain investigationofinvitrobiologicalpotentialofmethanolextractofmagnoliaalbaleaves
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