Immunological biomarkers in autism: a review
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020.
| 主要作者: | |
|---|---|
| 其他作者: | |
| 格式: | Thesis |
| 語言: | English |
| 出版: |
Brac University
2021
|
| 主題: | |
| 在線閱讀: | http://hdl.handle.net/10361/14739 |
| id |
10361-14739 |
|---|---|
| record_format |
dspace |
| spelling |
10361-147392021-07-05T21:01:22Z Immunological biomarkers in autism: a review Chowdhury, Mishkat Ahmed Neelotpol, Sharmind Department of Pharmacy, Brac University Immune dysregulation Cytokine Immunoglobulin Chemokine Autism. This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 32-43). Autism spectrum disorder (ASD) is a specific heterogenous neurodevelopmental disorder focused on the occurrence and intensity of core anomalies in social contact and repetitive behaviour, with complex pathogenesis and diagnosis. However, investigations have linked immune dysregulation as a hallmark of ASD. The prime justification for this claim lies in the numerous studies in the last four decades which found a frequent impaired immune response in individual with ASD. The aim of this review is to identify some immunological biomarker to investigate immune dysfunction in the diagnosis and treatment of ASD. Many studies have documented several immune cell abnormalities in ASD subjects, namely T-cells, B-cells, natural killer cells, and monocytes. Additionally, impairment in immunoglobulin regulation, chemokine activities and elevated autoantibodies production have been reported in many analyses. On top of that elevated peripheral cytokines, and chemokines and related neuroinflammation have been observed in a substantial chunk of individual diagnosed with ASD. Mishkat Ahmed Chowdhury B. Pharmacy 2021-07-05T15:46:32Z 2021-07-05T15:46:32Z 2020 2020-12 Thesis ID 16346048 http://hdl.handle.net/10361/14739 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 43 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Immune dysregulation Cytokine Immunoglobulin Chemokine Autism. |
| spellingShingle |
Immune dysregulation Cytokine Immunoglobulin Chemokine Autism. Chowdhury, Mishkat Ahmed Immunological biomarkers in autism: a review |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. |
| author2 |
Neelotpol, Sharmind |
| author_facet |
Neelotpol, Sharmind Chowdhury, Mishkat Ahmed |
| format |
Thesis |
| author |
Chowdhury, Mishkat Ahmed |
| author_sort |
Chowdhury, Mishkat Ahmed |
| title |
Immunological biomarkers in autism: a review |
| title_short |
Immunological biomarkers in autism: a review |
| title_full |
Immunological biomarkers in autism: a review |
| title_fullStr |
Immunological biomarkers in autism: a review |
| title_full_unstemmed |
Immunological biomarkers in autism: a review |
| title_sort |
immunological biomarkers in autism: a review |
| publisher |
Brac University |
| publishDate |
2021 |
| url |
http://hdl.handle.net/10361/14739 |
| work_keys_str_mv |
AT chowdhurymishkatahmed immunologicalbiomarkersinautismareview |
| _version_ |
1814308965190729728 |