Delivery of Denosumab via Hollow Microneedle
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020.
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| Ձևաչափ: | Թեզիս |
| Լեզու: | en_US |
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Brac University
2021
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| Առցանց հասանելիություն: | http://hdl.handle.net/10361/14509 |
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10361-14509 |
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10361-145092021-06-09T21:01:19Z Delivery of Denosumab via Hollow Microneedle Bushra, Fariha Uddin, Md. Jasim Department of Pharmacy, Brac University Transdermal Hollow microneedle Osteoporosis Denosumab Skin This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 19-27). The emergence of transdermal drug delivery via hollow microneedle can be used to enhance the distribution of medications delivered through the skin. In this current study, in-vivo animal studies of denosumab were carried out which involved the use of hollow microneedle to draw a comparison with the painful injection for the treatment of osteoporosis. The in-vivo study of the hollow-microneedle mediated delivery of denosumab, a monoclonal antibody was conducted to investigate if there is any possibility of improvement in osteoporosis, which affects a significant segment of post-menopausal women. Hollow microneedles mediated denosumab deliveries showed a remarkable improvement as compared to traditional injections. In recent times, hollow microneedle has managed to receive special attention as a novel drug delivery system due to its nature of being minimally invasive across the skin. In conclusion, the hollow microneedles may prove to be of great assistance for widening the feasibility of delivery of a wide range of therapeutic entities. Fariha Bushra B. Pharmacy 2021-06-09T09:23:45Z 2021-06-09T09:23:45Z 2020 2020-02 Thesis ID: 16146024 http://hdl.handle.net/10361/14509 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 27 Pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
en_US |
| topic |
Transdermal Hollow microneedle Osteoporosis Denosumab Skin |
| spellingShingle |
Transdermal Hollow microneedle Osteoporosis Denosumab Skin Bushra, Fariha Delivery of Denosumab via Hollow Microneedle |
| description |
This thesis is submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy, 2020. |
| author2 |
Uddin, Md. Jasim |
| author_facet |
Uddin, Md. Jasim Bushra, Fariha |
| format |
Thesis |
| author |
Bushra, Fariha |
| author_sort |
Bushra, Fariha |
| title |
Delivery of Denosumab via Hollow Microneedle |
| title_short |
Delivery of Denosumab via Hollow Microneedle |
| title_full |
Delivery of Denosumab via Hollow Microneedle |
| title_fullStr |
Delivery of Denosumab via Hollow Microneedle |
| title_full_unstemmed |
Delivery of Denosumab via Hollow Microneedle |
| title_sort |
delivery of denosumab via hollow microneedle |
| publisher |
Brac University |
| publishDate |
2021 |
| url |
http://hdl.handle.net/10361/14509 |
| work_keys_str_mv |
AT bushrafariha deliveryofdenosumabviahollowmicroneedle |
| _version_ |
1814306990435860480 |