Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method

Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method

This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Science in Biotechnology 2020.

Bibliographic Details
Main Author: Tahsin, Anika
Other Authors: Hossain, M. Mahboob
Format: Thesis
Language:en_US
Published: Brac University 2021
Subjects:
Pharmacogenetics
SNP
CYP2C9 gene
Genotyping
Tetra-primer ARMS PCR
Online Access:http://dspace.bracu.ac.bd/xmlui/handle/10361/14433
id 10361-14433
record_format dspace
spelling 10361-144332021-05-27T21:01:15Z Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method Tahsin, Anika Hossain, M. Mahboob Akash, Md. Mahmudul Hasan Department of Mathematics and Natural Sciences, Brac University Pharmacogenetics SNP CYP2C9 gene Genotyping Tetra-primer ARMS PCR This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Science in Biotechnology 2020. Catalogued from PDF version of thesis. Includes bibliographical references (pages 52-56). Pharmacogenetics is the study of how similar drugs affect different people differently according to their unique genetic makeup as an individual. Pharmacogenetics includes a wide variety of research and discovery including essential medication disclosure, genetic research of pharmacokinetics as well as pharmacodynamics, new medication improvement and persistent hereditary testing where the final objective is to find out how a person’s gene is responding to different medications and find the best possible treatment for that individual or that group of individuals. By foreseeing the medication reaction of an individual, it will be conceivable to build the accomplishment of treatments and decrease the rate of unfavorable symptoms.In this research, our primary intent is to develop a SNP genotyping method for a particular drug, which is a sulfonylureas drug in the case of type 1 diabetes, and how it affects the functionality of CYP2C9 gene in human body. Finally, our goal is to identify whether our desired SNP is present in the particular locus using the Tetra primer ARMS PCR technique and design the drug dose of that patient accordingly Anika Tahsin B. Biotechnology 2021-05-27T08:31:32Z 2021-05-27T08:31:32Z 2020 2020-08 Thesis ID: 16136030 http://dspace.bracu.ac.bd/xmlui/handle/10361/14433 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 56 pages application/pdf Brac University
institution Brac University
collection Institutional Repository
language en_US
topic Pharmacogenetics
SNP
CYP2C9 gene
Genotyping
Tetra-primer ARMS PCR
spellingShingle Pharmacogenetics
SNP
CYP2C9 gene
Genotyping
Tetra-primer ARMS PCR
Tahsin, Anika
Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method
description This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Science in Biotechnology 2020.
author2 Hossain, M. Mahboob
author_facet Hossain, M. Mahboob
Tahsin, Anika
format Thesis
author Tahsin, Anika
author_sort Tahsin, Anika
title Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method
title_short Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method
title_full Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method
title_fullStr Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method
title_full_unstemmed Genotyping of a Clinically Important SNP rs1799853 Present in the CYP2C9 Gene Using Tetra-primer ARMS PCR Method
title_sort genotyping of a clinically important snp rs1799853 present in the cyp2c9 gene using tetra-primer arms pcr method
publisher Brac University
publishDate 2021
url http://dspace.bracu.ac.bd/xmlui/handle/10361/14433
work_keys_str_mv AT tahsinanika genotypingofaclinicallyimportantsnprs1799853presentinthecyp2c9geneusingtetraprimerarmspcrmethod
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