CRISPR/Cas9 system: A versatile gene editing tool in disease prevention and treatment
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.
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Brac University
2020
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| Online toegang: | http://hdl.handle.net/10361/14026 |
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10361-140262020-08-31T21:01:17Z CRISPR/Cas9 system: A versatile gene editing tool in disease prevention and treatment Maria, Amatul Afrose, Dr. Afrina Department of Pharmacy, Brac University CRISPR Cas9 Gene editing tool Genome editing This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 33-42). With the development of genome editing as a promising mechanism for disease prevention and treatment, clustered regularly interspaced short palindromic repeats (CRISPR) is a robust and multiplexed tool that is able to address the challenges faced by its predecessors such as ZincFinger Nucleases (ZFNs) and Transcription Activator-like Effector Nuclease (TALENs). The findings indicate that CRISPR-Cas9 is more precise, convenient and cost effective in comparison with its forerunners in terms of DNA cleavage. Recent advancements of this tool have enabled researchers and scientists to adopt treatment options for diseases like cancer, AIDS, muscular dystrophy, blood disorders, cystic fibrosis, Huntington’s disease etc. Despite massive potential of this tool to detect and modify genes responsible for various diseases, human trials remain the most controversial factor in scientific community and academia. Hence, more research is needed to explore more possibilities and fill the gaps in information that can prove to be crucial for achieving desired outcomes in disease prevention and treatment. Amatul Maria B. Pharmacy 2020-08-31T15:23:18Z 2020-08-31T15:23:18Z 2019 2019-10 Thesis ID 14246006 http://hdl.handle.net/10361/14026 en_US Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 42 pages application/pdf Brac University |
| institution |
Brac University |
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Institutional Repository |
| language |
en_US |
| topic |
CRISPR Cas9 Gene editing tool Genome editing |
| spellingShingle |
CRISPR Cas9 Gene editing tool Genome editing Maria, Amatul CRISPR/Cas9 system: A versatile gene editing tool in disease prevention and treatment |
| description |
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. |
| author2 |
Afrose, Dr. Afrina |
| author_facet |
Afrose, Dr. Afrina Maria, Amatul |
| format |
Thesis |
| author |
Maria, Amatul |
| author_sort |
Maria, Amatul |
| title |
CRISPR/Cas9 system: A versatile gene editing tool in disease prevention and treatment |
| title_short |
CRISPR/Cas9 system: A versatile gene editing tool in disease prevention and treatment |
| title_full |
CRISPR/Cas9 system: A versatile gene editing tool in disease prevention and treatment |
| title_fullStr |
CRISPR/Cas9 system: A versatile gene editing tool in disease prevention and treatment |
| title_full_unstemmed |
CRISPR/Cas9 system: A versatile gene editing tool in disease prevention and treatment |
| title_sort |
crispr/cas9 system: a versatile gene editing tool in disease prevention and treatment |
| publisher |
Brac University |
| publishDate |
2020 |
| url |
http://hdl.handle.net/10361/14026 |
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AT mariaamatul crisprcas9systemaversatilegeneeditingtoolindiseasepreventionandtreatment |
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