Method development of oil solubility test of Aceclofenac
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.
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Brac University
2020
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| Länkar: | http://hdl.handle.net/10361/13935 |
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10361-13935 |
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10361-139352020-08-11T21:01:14Z Method development of oil solubility test of Aceclofenac Ray, Joytee Chowdhury, Namara Mariam Department of Pharmacy, Brac University Nanoemulsion Solubility Aceclofenac Extraction of oil Hexane layer Medicine This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 34-42). The aim of the study was to develop a method that would allow the solubility testing of Aceclofenac in different oils. The main target was to find a suitable method by using commercially available drugs like olive oil. The process involved screening of oil after which extraction was done in a separating funnel in order to differentiate the API using hexane and methanol. The absorbance was taken in UV spectrophotometer and wavelength scan of hexane layer was found out. Series of extraction was done to see up to how many extractions were needed until there was no more API peak in the hexane layer and all the Aceclofenac was dissolved in methanol layer. The results showed that, after 10 times extraction the absorbance of the methanol layer at 277 nm came out 0.78 which falls within the ideal range 0.5-1 and no peak was seen in the hexane layer within the wavelength range. Joytee Ray B. Pharmacy 2020-08-11T11:58:18Z 2020-08-11T11:58:18Z 2019 2019-10 Thesis ID 15346016 http://hdl.handle.net/10361/13935 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 42 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Nanoemulsion Solubility Aceclofenac Extraction of oil Hexane layer Medicine |
| spellingShingle |
Nanoemulsion Solubility Aceclofenac Extraction of oil Hexane layer Medicine Ray, Joytee Method development of oil solubility test of Aceclofenac |
| description |
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. |
| author2 |
Chowdhury, Namara Mariam |
| author_facet |
Chowdhury, Namara Mariam Ray, Joytee |
| format |
Thesis |
| author |
Ray, Joytee |
| author_sort |
Ray, Joytee |
| title |
Method development of oil solubility test of Aceclofenac |
| title_short |
Method development of oil solubility test of Aceclofenac |
| title_full |
Method development of oil solubility test of Aceclofenac |
| title_fullStr |
Method development of oil solubility test of Aceclofenac |
| title_full_unstemmed |
Method development of oil solubility test of Aceclofenac |
| title_sort |
method development of oil solubility test of aceclofenac |
| publisher |
Brac University |
| publishDate |
2020 |
| url |
http://hdl.handle.net/10361/13935 |
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AT rayjoytee methoddevelopmentofoilsolubilitytestofaceclofenac |
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