An in-vivo study on anti-emetic and in-vitro study on anthelmintic properties of cassia fistula
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.
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Brac University
2020
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| Mynediad Ar-lein: | http://hdl.handle.net/10361/13930 |
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10361-139302020-08-10T21:01:15Z An in-vivo study on anti-emetic and in-vitro study on anthelmintic properties of cassia fistula Adrita, Tasnuva Shahreen Tahsin, Faria Department of Pharmacy, Brac University Cassia fistula Emesis Retching Anthelmintic Paralysis Materia medica, Vegetable This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 26-28). Cassia fistula is a tropical and sub-tropical legume tree which is widely known for its antioxidant, anti-inflammaory, antitumor, hypolipidemic, antimicrobial, hepato-protective and many pharmacological activities. The present study focuses on the investigation of antiemetic and anthelmintic activity of crude methanolic extract of Cassia fistula using 2-4 days chicks (32-52gm) model and Pheretima posthuma model respectively. The chick samples were administered with copper sulphate by oral route of administration to initiate emesis among them. Afterwards they were administered with leaf extract (150 mg/kg) orally which exhibited significant antiemetic property (61.58%, 88.41% and 30.79%) compared with reference drug chlorpromazine (29.88%). In-vitro anthelmintic tests were done with earthworms (Pheretima posthuma) by using Cassia fistula leaf extract of different concentrations (60 mg/mL, 80 mg/mL and 100 mg/mL). Albendazole (20 mg/mL) was included as a standard reference and for control distilled water was used. The two concentrations of Cassia fistula extract which were 80 mg/mL and 100 mg/mL exhibited significant results which were superior than the standard used (albendazole). Tasnuva Shahreen Adrita B. Pharmacy 2020-08-10T11:42:39Z 2020-08-10T11:42:39Z 2019 2019-08 Thesis ID 15146093 http://hdl.handle.net/10361/13930 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 28 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Cassia fistula Emesis Retching Anthelmintic Paralysis Materia medica, Vegetable |
| spellingShingle |
Cassia fistula Emesis Retching Anthelmintic Paralysis Materia medica, Vegetable Adrita, Tasnuva Shahreen An in-vivo study on anti-emetic and in-vitro study on anthelmintic properties of cassia fistula |
| description |
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. |
| author2 |
Tahsin, Faria |
| author_facet |
Tahsin, Faria Adrita, Tasnuva Shahreen |
| format |
Thesis |
| author |
Adrita, Tasnuva Shahreen |
| author_sort |
Adrita, Tasnuva Shahreen |
| title |
An in-vivo study on anti-emetic and in-vitro study on anthelmintic properties of cassia fistula |
| title_short |
An in-vivo study on anti-emetic and in-vitro study on anthelmintic properties of cassia fistula |
| title_full |
An in-vivo study on anti-emetic and in-vitro study on anthelmintic properties of cassia fistula |
| title_fullStr |
An in-vivo study on anti-emetic and in-vitro study on anthelmintic properties of cassia fistula |
| title_full_unstemmed |
An in-vivo study on anti-emetic and in-vitro study on anthelmintic properties of cassia fistula |
| title_sort |
in-vivo study on anti-emetic and in-vitro study on anthelmintic properties of cassia fistula |
| publisher |
Brac University |
| publishDate |
2020 |
| url |
http://hdl.handle.net/10361/13930 |
| work_keys_str_mv |
AT adritatasnuvashahreen aninvivostudyonantiemeticandinvitrostudyonanthelminticpropertiesofcassiafistula AT adritatasnuvashahreen invivostudyonantiemeticandinvitrostudyonanthelminticpropertiesofcassiafistula |
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1814308321453146112 |