Progress of finding latent therapeutic activity of vaccine for Alzheimer’s disease
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.
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Brac University
2020
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Առցանց հասանելիություն: | http://hdl.handle.net/10361/13908 |
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10361-139082020-08-06T21:01:23Z Progress of finding latent therapeutic activity of vaccine for Alzheimer’s disease Hassan, Md. Muhtaz Kabir, Md. Tanvir Department of Pharmacy, Brac University Amyloid-β Neurofibrillary tangles Senile plaque Active vaccination Passive vaccination Alzheimer’s disease Alzheimer's disease--Vaccination This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 62-84). Alzheimer’s disease is one of leading diseases which provokes different internal physiological conditions that ease deterioration of normal body mechanism among people over 60 years of age. The proper pathophysiology of this disease is still undiscovered. There are two neuropathological hallmarks for this deadliest disease, among them one is amyloid-β and another is senile plaque deposition which plays extracellular role, on the other side neurofibrillary tangles which contain hyperphosphorylated tau protein dominate intracellular portion. A variety of medicinal approaches have been experimented targeting amyloid-β among them the most innovative approaches were reducing amyloid-β from the brain by active and passive vaccination. Since the first approach, a number of vaccines have been stopped during clinical trials and some are still under investigation. Different co-relating possibilities are merging together to initiate a proper medicinal pathway along with the invention of the specific pathophysiology of this disease. Md. Muhtaz Hassan B. Pharmacy 2020-08-06T10:31:37Z 2020-08-06T10:31:37Z 2019 2019-05 Thesis ID 10246002 http://hdl.handle.net/10361/13908 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 84 pages application/pdf Brac University |
institution |
Brac University |
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Institutional Repository |
language |
English |
topic |
Amyloid-β Neurofibrillary tangles Senile plaque Active vaccination Passive vaccination Alzheimer’s disease Alzheimer's disease--Vaccination |
spellingShingle |
Amyloid-β Neurofibrillary tangles Senile plaque Active vaccination Passive vaccination Alzheimer’s disease Alzheimer's disease--Vaccination Hassan, Md. Muhtaz Progress of finding latent therapeutic activity of vaccine for Alzheimer’s disease |
description |
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. |
author2 |
Kabir, Md. Tanvir |
author_facet |
Kabir, Md. Tanvir Hassan, Md. Muhtaz |
format |
Thesis |
author |
Hassan, Md. Muhtaz |
author_sort |
Hassan, Md. Muhtaz |
title |
Progress of finding latent therapeutic activity of vaccine for Alzheimer’s disease |
title_short |
Progress of finding latent therapeutic activity of vaccine for Alzheimer’s disease |
title_full |
Progress of finding latent therapeutic activity of vaccine for Alzheimer’s disease |
title_fullStr |
Progress of finding latent therapeutic activity of vaccine for Alzheimer’s disease |
title_full_unstemmed |
Progress of finding latent therapeutic activity of vaccine for Alzheimer’s disease |
title_sort |
progress of finding latent therapeutic activity of vaccine for alzheimer’s disease |
publisher |
Brac University |
publishDate |
2020 |
url |
http://hdl.handle.net/10361/13908 |
work_keys_str_mv |
AT hassanmdmuhtaz progressoffindinglatenttherapeuticactivityofvaccineforalzheimersdisease |
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1814309358407778304 |