Effects of Allium sativum extract in arsenic induced toxicity in Swiss albino mice
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.
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| Materyal Türü: | Tez |
| Dil: | English |
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Brac University
2020
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| Online Erişim: | http://hdl.handle.net/10361/13686 |
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10361-13686 |
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10361-136862020-01-30T21:01:13Z Effects of Allium sativum extract in arsenic induced toxicity in Swiss albino mice Adhara, Rusafa Antashin Akter, Rausahanara Department of Pharmacy, Brac University Arsenicosis Allium sativum Biochemical parameters Toxic Chelation Antioxidant Garlic Haematological parameters Detox This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 63-70). Arsenic (As) is metal toxic element to the body and it is available in environment. Arsenicosis, elevated level of As in body, can be treated by chelation therapy. In chelation therapy, a chelate is used to form a complex chemical structure with the metal ion. As, Allium sativumis a natural chelate and this study focuses on the in vivo evaluation of the chelating effect of Allium sativum(methanolic extract) of different doses (150, 300, 500 mg/kg) on the depletion of arsenic from the cellular level, using Swiss albino mice. Body weight, hematological and biochemical parameters like, WBC, RBC, NEU, ALP, CRE, cellular structure of skin, brain, kidney, liver were observed and significant amount of changes were found. Allium sativa, popularly known as the garlic, is an influential antioxidant that, have the potential to detox the body via its chelating characteristics by absorbing toxic substances or metal sections. Rusafa Antashin Adhara B. Pharmacy 2020-01-30T04:08:30Z 2020-01-30T04:08:30Z 2019 2019-08 Thesis ID 14346006 http://hdl.handle.net/10361/13686 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 70 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Arsenicosis Allium sativum Biochemical parameters Toxic Chelation Antioxidant Garlic Haematological parameters Detox |
| spellingShingle |
Arsenicosis Allium sativum Biochemical parameters Toxic Chelation Antioxidant Garlic Haematological parameters Detox Adhara, Rusafa Antashin Effects of Allium sativum extract in arsenic induced toxicity in Swiss albino mice |
| description |
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. |
| author2 |
Akter, Rausahanara |
| author_facet |
Akter, Rausahanara Adhara, Rusafa Antashin |
| format |
Thesis |
| author |
Adhara, Rusafa Antashin |
| author_sort |
Adhara, Rusafa Antashin |
| title |
Effects of Allium sativum extract in arsenic induced toxicity in Swiss albino mice |
| title_short |
Effects of Allium sativum extract in arsenic induced toxicity in Swiss albino mice |
| title_full |
Effects of Allium sativum extract in arsenic induced toxicity in Swiss albino mice |
| title_fullStr |
Effects of Allium sativum extract in arsenic induced toxicity in Swiss albino mice |
| title_full_unstemmed |
Effects of Allium sativum extract in arsenic induced toxicity in Swiss albino mice |
| title_sort |
effects of allium sativum extract in arsenic induced toxicity in swiss albino mice |
| publisher |
Brac University |
| publishDate |
2020 |
| url |
http://hdl.handle.net/10361/13686 |
| work_keys_str_mv |
AT adhararusafaantashin effectsofalliumsativumextractinarsenicinducedtoxicityinswissalbinomice |
| _version_ |
1814308546904326144 |