Hot melt extrusion: a state of the art and multifunctional technique for oral film formulation
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.
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Brac University
2020
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| Accés en línia: | http://hdl.handle.net/10361/13682 |
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10361-136822020-01-28T21:01:09Z Hot melt extrusion: a state of the art and multifunctional technique for oral film formulation Taheya, Rezwana Tabassum Uddin, Md. Jasim Department of Pharmacy, Brac University Oral thin film Hot melt extrusion Taste masking This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. Cataloged from PDF version of thesis report. Includes bibliographical references (pages 36-45). Hot melt extrusion (HME) is one of the most extensively studied techniques for pharmaceutical application. Several researchers have been trying to establish this potential method in oral thin film (OTF) formulation and hundreds research articles have been published on this noble approach. OTF is an emerging dosage form in pharmaceutical field and HME is a promising technology in film formulation. HME is advantageous over other methods since it is a one-step method, does not require solvents; it has showed taste masking capability by solid dispersion and has showed improved bioavailability of drugs. Moreover, the scale up process not being problematic it can be employed on commercial scale production. This review has 3 major objectives. Firstly, it gives an overview on oral thin film and HME technology in formulation of thin film. Secondly, it shows the importance of taste masking and HME in taste masking. Lastly, it discusses multi-functionality of HME in combination of other techniques like 3D printing, co-extrusion and nanotechnology. Rezwana Tabassum Taheya B. Pharmacy 2020-01-28T09:07:55Z 2020-01-28T09:07:55Z 2019 2019-08 Thesis ID 14146034 http://hdl.handle.net/10361/13682 en Brac University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 45 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Oral thin film Hot melt extrusion Taste masking |
| spellingShingle |
Oral thin film Hot melt extrusion Taste masking Taheya, Rezwana Tabassum Hot melt extrusion: a state of the art and multifunctional technique for oral film formulation |
| description |
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. |
| author2 |
Uddin, Md. Jasim |
| author_facet |
Uddin, Md. Jasim Taheya, Rezwana Tabassum |
| format |
Thesis |
| author |
Taheya, Rezwana Tabassum |
| author_sort |
Taheya, Rezwana Tabassum |
| title |
Hot melt extrusion: a state of the art and multifunctional technique for oral film formulation |
| title_short |
Hot melt extrusion: a state of the art and multifunctional technique for oral film formulation |
| title_full |
Hot melt extrusion: a state of the art and multifunctional technique for oral film formulation |
| title_fullStr |
Hot melt extrusion: a state of the art and multifunctional technique for oral film formulation |
| title_full_unstemmed |
Hot melt extrusion: a state of the art and multifunctional technique for oral film formulation |
| title_sort |
hot melt extrusion: a state of the art and multifunctional technique for oral film formulation |
| publisher |
Brac University |
| publishDate |
2020 |
| url |
http://hdl.handle.net/10361/13682 |
| work_keys_str_mv |
AT taheyarezwanatabassum hotmeltextrusionastateoftheartandmultifunctionaltechniquefororalfilmformulation |
| _version_ |
1814309043815055360 |