Solubility profile of linagliptin: designing of transdermal formulation

This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.

Bibliographic Details
Main Author:	Hossain, Md. Kaykobad
Other Authors:	Kabir, Eva Rahman
Format:	Project report
Language:	English
Published:	Brac University 2019
Subjects:	Diabetes mellitus Linagliptin Solubility profile Shake-flask method Transdermal route Diabetes
Online Access:	http://hdl.handle.net/10361/12801

id	10361-12801
record_format	dspace
spelling	10361-128012019-10-23T21:01:07Z Solubility profile of linagliptin: designing of transdermal formulation Hossain, Md. Kaykobad Kabir, Eva Rahman Department of Pharmacy, Brac University Diabetes mellitus Linagliptin Solubility profile Shake-flask method Transdermal route Diabetes This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019. Cataloged from PDF version of project report. Includes bibliographical references (pages 39-47). Diabetes mellitus is a common disease in current world and according to a report of 2013, 8.3% of total adult population is suffering from this disease, with diabetes mellitus type two making up 90% of the cases. There are many anti-diabetic agents available which are administered through oral and parenteral routes. One common oral agent is Linagliptin which is a dipeptidyl peptidase-4 (DPP-4) inhibitor. But oral bioavailability of this drug is only 30%, which suggests the introduction of other routes of drug delivery. Transdermal delivery of this drug might be a good choice, but before designing the formulation, solubility profile of this drug should be determined. This needs to be done to determine the solvent or co-solvent to be used and also to get the idea about the concentration of the drug that can be used. One of the most common methods of solubility determination is shake-flask method which was used in this study. Md. Kaykobad Hossain B. Pharmacy 2019-10-23T06:20:03Z 2019-10-23T06:20:03Z 2019 2019-05 Project report ID 15146065 http://hdl.handle.net/10361/12801 en Brac University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 47 pages application/pdf Brac University
institution	Brac University
collection	Institutional Repository
language	English
topic	Diabetes mellitus Linagliptin Solubility profile Shake-flask method Transdermal route Diabetes
spellingShingle	Diabetes mellitus Linagliptin Solubility profile Shake-flask method Transdermal route Diabetes Hossain, Md. Kaykobad Solubility profile of linagliptin: designing of transdermal formulation
description	This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2019.
author2	Kabir, Eva Rahman
author_facet	Kabir, Eva Rahman Hossain, Md. Kaykobad
format	Project report
author	Hossain, Md. Kaykobad
author_sort	Hossain, Md. Kaykobad
title	Solubility profile of linagliptin: designing of transdermal formulation
title_short	Solubility profile of linagliptin: designing of transdermal formulation
title_full	Solubility profile of linagliptin: designing of transdermal formulation
title_fullStr	Solubility profile of linagliptin: designing of transdermal formulation
title_full_unstemmed	Solubility profile of linagliptin: designing of transdermal formulation
title_sort	solubility profile of linagliptin: designing of transdermal formulation
publisher	Brac University
publishDate	2019
url	http://hdl.handle.net/10361/12801
work_keys_str_mv	AT hossainmdkaykobad solubilityprofileoflinagliptindesigningoftransdermalformulation
_version_	1814309112565989376

Solubility profile of linagliptin: designing of transdermal formulation

Similar Items