Recent developments in the Adeno-Associated Viral Gene Therapy for Non-Small Cell Lung Cancer during the past 20 years
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018.
| 主要作者: | |
|---|---|
| 其他作者: | |
| 格式: | Thesis |
| 语言: | English |
| 出版: |
Brac University
2019
|
| 主题: | |
| 在线阅读: | http://hdl.handle.net/10361/12766 |
| id |
10361-12766 |
|---|---|
| record_format |
dspace |
| spelling |
10361-127662019-10-02T02:59:24Z Recent developments in the Adeno-Associated Viral Gene Therapy for Non-Small Cell Lung Cancer during the past 20 years Razna, Amrin Islam Khan, Rubayat Islam Department of Pharmacy, Brac University Adeno-associated virus Lung Cancer Immune system Lungs--Cancer. Gene therapy. This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. Cataloged from PDF version of project report. Includes bibliographical references (pages 55-59). Gene therapy has a diverse plethora of applications. Many genetic diseases – including both dominant gain-of-functions diseases and recessive conditions have an equal opportunity to be cured by it. In this study, the treatment of non-small cell lung cancer with the help of gene therapy using adeno-associated virus (AAV) vector is the focal point. Non-small cell lung cancer requires multiple drugs for effective treatment. In spite of this the survival rate is low compared to other forms of cancer. In addition to this, the choice of drugs and methods of treatment greatly depends on the health of the patient. Gene therapy is considered to be an ideal treatment in this study. It not only cures the condition from the root level but also can be applied to all patient types. AAV is used in place of adenovirus, in the light that even though its onset of action is slow, its duration of action is greater. Many techniques of gene therapy have been covered in this review. These include CRISPR-Cas9 technology, zinc-finger nuclease, splicosome-mediated RNA trans-splicing, RNA interference technique, antisense-oligonucleotide therapy. The future of gene therapy can be promising if these techniques could become more developed by thorough and rigorous experimentation to refine their methodologies. Amrin Islam Razna B. Pharmacy 2019-10-01T04:16:27Z 2019-10-01T04:16:27Z 2018 2013 Thesis ID 13346019 http://hdl.handle.net/10361/12766 en 62 pages application/pdf Brac University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Adeno-associated virus Lung Cancer Immune system Lungs--Cancer. Gene therapy. |
| spellingShingle |
Adeno-associated virus Lung Cancer Immune system Lungs--Cancer. Gene therapy. Razna, Amrin Islam Recent developments in the Adeno-Associated Viral Gene Therapy for Non-Small Cell Lung Cancer during the past 20 years |
| description |
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. |
| author2 |
Khan, Rubayat Islam |
| author_facet |
Khan, Rubayat Islam Razna, Amrin Islam |
| format |
Thesis |
| author |
Razna, Amrin Islam |
| author_sort |
Razna, Amrin Islam |
| title |
Recent developments in the Adeno-Associated Viral Gene Therapy for Non-Small Cell Lung Cancer during the past 20 years |
| title_short |
Recent developments in the Adeno-Associated Viral Gene Therapy for Non-Small Cell Lung Cancer during the past 20 years |
| title_full |
Recent developments in the Adeno-Associated Viral Gene Therapy for Non-Small Cell Lung Cancer during the past 20 years |
| title_fullStr |
Recent developments in the Adeno-Associated Viral Gene Therapy for Non-Small Cell Lung Cancer during the past 20 years |
| title_full_unstemmed |
Recent developments in the Adeno-Associated Viral Gene Therapy for Non-Small Cell Lung Cancer during the past 20 years |
| title_sort |
recent developments in the adeno-associated viral gene therapy for non-small cell lung cancer during the past 20 years |
| publisher |
Brac University |
| publishDate |
2019 |
| url |
http://hdl.handle.net/10361/12766 |
| work_keys_str_mv |
AT raznaamrinislam recentdevelopmentsintheadenoassociatedviralgenetherapyfornonsmallcelllungcancerduringthepast20years |
| _version_ |
1814308681273049088 |