Phytochemical and biological evaluation of methanolic extract of Boehmeria macrophylla leaves
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018.
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| Định dạng: | Project report |
| Ngôn ngữ: | English |
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BRAC University
2019
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| Truy cập trực tuyến: | http://hdl.handle.net/10361/11069 |
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10361-11069 |
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10361-110692019-09-30T04:55:10Z Phytochemical and biological evaluation of methanolic extract of Boehmeria macrophylla leaves Tahmid, Tasin Brishty, Shejuti Rahman Department of Pharmacy, BRAC University Biological evaluation Phytochemical evaluation Boehmeria macrophylla This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. Catalogued from PDF version of project report. Includes bibliographical references (page 40-42). The present study has been designed to test and establish the scientific basis of the use of Boehmeria macrophylla as potential therapeutic agent in traditional medicine in Bangladesh. The methanolic extract of leaves of Boehmeria macrophylla was chosen for phytochemical screening and in vitro biological evaluation for the first time. The preliminary phytochemical screening revealed the presence of carbohydrates, phenols, phytosterols, glycosides and saponin in the crude methanolic extract of the plant. The leaf extract showed noteworthy antioxidant activities through DPPH free radical scavenging assay, along with its total phenolic content, flavonoid content and antioxidant capacity. Moreover, moderate cytotoxic effect in brine shrimp lethality bioassay was also observed. Antimicrobial activity was evaluated by disc diffusion method and the result showed maximum activity against Bacillus subtilis. Increasing concentration of the methanolic extract may help establish its potential against other microorganisms. Additionally, thrombolytic activity was tested using Streptokinase which further presented the plant extract as a mild thrombolytic agent. Future investigations on this plant may help in the development of new drugs and also aid in the research of combination drugs to treat a wide variety of diseases in Bangladesh as well as around the world. Tasin Tahmid B. Pharmacy 2019-01-02T08:11:08Z 2019-01-02T08:11:08Z 2017 2017-12 Project report ID 13146040 http://hdl.handle.net/10361/11069 en BRAC University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 42 pages application/pdf BRAC University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Biological evaluation Phytochemical evaluation Boehmeria macrophylla |
| spellingShingle |
Biological evaluation Phytochemical evaluation Boehmeria macrophylla Tahmid, Tasin Phytochemical and biological evaluation of methanolic extract of Boehmeria macrophylla leaves |
| description |
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. |
| author2 |
Brishty, Shejuti Rahman |
| author_facet |
Brishty, Shejuti Rahman Tahmid, Tasin |
| format |
Project report |
| author |
Tahmid, Tasin |
| author_sort |
Tahmid, Tasin |
| title |
Phytochemical and biological evaluation of methanolic extract of Boehmeria macrophylla leaves |
| title_short |
Phytochemical and biological evaluation of methanolic extract of Boehmeria macrophylla leaves |
| title_full |
Phytochemical and biological evaluation of methanolic extract of Boehmeria macrophylla leaves |
| title_fullStr |
Phytochemical and biological evaluation of methanolic extract of Boehmeria macrophylla leaves |
| title_full_unstemmed |
Phytochemical and biological evaluation of methanolic extract of Boehmeria macrophylla leaves |
| title_sort |
phytochemical and biological evaluation of methanolic extract of boehmeria macrophylla leaves |
| publisher |
BRAC University |
| publishDate |
2019 |
| url |
http://hdl.handle.net/10361/11069 |
| work_keys_str_mv |
AT tahmidtasin phytochemicalandbiologicalevaluationofmethanolicextractofboehmeriamacrophyllaleaves |
| _version_ |
1814306827175723008 |