Practice of geophagy: effects of calabash chalk on liver, kidney and spleen in swiss albino rats
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018.
| Auteur principal: | |
|---|---|
| Autres auteurs: | |
| Format: | Project report |
| Langue: | English |
| Publié: |
BRAC University
2019
|
| Sujets: | |
| Accès en ligne: | http://hdl.handle.net/10361/11068 |
| id |
10361-11068 |
|---|---|
| record_format |
dspace |
| spelling |
10361-110682019-09-30T04:55:12Z Practice of geophagy: effects of calabash chalk on liver, kidney and spleen in swiss albino rats Khan, Farzana Neelotpol, Dr. Sharmind Department of Pharmacy, BRAC University Calabash chalk Pregnancy Food habits--Psychological aspects. This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. Catalogued from PDF version of project report. Includes bibliographical references (page 29-35). Geophagy is the practice of consuming earth materials such as Calabash chalk. This practice is widespread in diverse countries in Asia and Africa by both the sexes and the different age groups of people. Many women and children who ingest Calabash chalk develop dependency. Many pregnant women take Calabash chalk as a remedy from morning sickness and some people also take it to lessen stomach dressing. However, harmful contents of calabash chalk such as Lead, Aluminum Silicate Hydroxide were found responsible for affecting developing brain of fetus and also, they affect the kidneys, nervous system, and reproductive system. Therefore, the aim of this study is to evaluate the effect of Calabash chalk on the biochemical and histopathological changes in spleen, kidney and liver of second generation Albino Rats. To conduct this study four groups of rats were treated with only water and 0.5ml, 1.0ml and 1.ml dose of Calabash Chalk. After 33 days blood and organ samples were collected for further examination. In this study, although no significant results were found in case of blood parameters, several changes such as possible hepatocellular injury in kidney cells and sinusoidal dilution in liver cells were found in rats due to the treatment with Calabash Chalk. Cellular carcinoma was also suspected in spleen cells. Farzana Khan B. Pharmacy 2019-01-02T07:58:15Z 2019-01-02T07:58:15Z 2018 2018-02 Project report ID 13146039 http://hdl.handle.net/10361/11068 en BRAC University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 35 pages application/pdf BRAC University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Calabash chalk Pregnancy Food habits--Psychological aspects. |
| spellingShingle |
Calabash chalk Pregnancy Food habits--Psychological aspects. Khan, Farzana Practice of geophagy: effects of calabash chalk on liver, kidney and spleen in swiss albino rats |
| description |
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. |
| author2 |
Neelotpol, Dr. Sharmind |
| author_facet |
Neelotpol, Dr. Sharmind Khan, Farzana |
| format |
Project report |
| author |
Khan, Farzana |
| author_sort |
Khan, Farzana |
| title |
Practice of geophagy: effects of calabash chalk on liver, kidney and spleen in swiss albino rats |
| title_short |
Practice of geophagy: effects of calabash chalk on liver, kidney and spleen in swiss albino rats |
| title_full |
Practice of geophagy: effects of calabash chalk on liver, kidney and spleen in swiss albino rats |
| title_fullStr |
Practice of geophagy: effects of calabash chalk on liver, kidney and spleen in swiss albino rats |
| title_full_unstemmed |
Practice of geophagy: effects of calabash chalk on liver, kidney and spleen in swiss albino rats |
| title_sort |
practice of geophagy: effects of calabash chalk on liver, kidney and spleen in swiss albino rats |
| publisher |
BRAC University |
| publishDate |
2019 |
| url |
http://hdl.handle.net/10361/11068 |
| work_keys_str_mv |
AT khanfarzana practiceofgeophagyeffectsofcalabashchalkonliverkidneyandspleeninswissalbinorats |
| _version_ |
1814307627763499008 |