Phytochemical screening and biological activity evaluation of Hygrophila schulli
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018.
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BRAC University
2018
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| 在線閱讀: | http://hdl.handle.net/10361/10936 |
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10361-109362019-09-30T06:14:57Z Phytochemical screening and biological activity evaluation of Hygrophila schulli Shoma, Fauzia Karim Rahman, Monica Sharfin Department of Pharmacy, BRAC University Hygrophila schulli Phytochemical screening This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. Catalogued from PDF version of project report. Includes bibliographical references (page 65-71). Hygrophila schulli (Family: Acanthaceae) is a crucial medicinal plant which is commonly habitat in the sub continental zone. The plant is frequently used in the Indian Ayurveda system for the treatment of urogenital tract diseases such as in dysuria, urinary calculi and cystitis due to its diuretic property. Moreover, the plant has also established its significant potentiality in treating kidney stone in the folk medicine system. In spite of its strong medicinal value, only sporadic attempts have been made for the scientific and methodical validation of these traditional uses. The current investigation aimed to determine the phytochemical constituents as well as to evaluate antioxidant, antimicrobial and cytotoxic potentials of the methanolic extract of this plant. The investigation revealed the presence of several phytochemical compounds namely, alkaloids, flavonoids, phenols, glycosides, tannins and steroids. The antioxidant potential of the plant was evaluated by means of DPPH assay and total phenolic content assay. Both the assay showed significant antioxidant potential of this plant. It draws a fine line to use H. schulli in cardiovascular and antiinflammatory diseases. Brine shrimp lethality bioassay was also performed on this plant, which showed a dose dependent relationship of concentration and % mortality of shrimp nauplii. In this study, the LC50 values of the standard, vincristine sulphate and methanolic extract of H. schulli were obtained 1.115 g/mL and 294.182 g/mL respectively. However, the crude methanolic extract as well as the pet ether fraction, chloroform fraction, ethyl acetate fraction and aqueous fraction of H. schulli showed no sensitivity in antimicrobial assay. Based on these investigations, it may be suggest that the plant H. schulli can be used as a potential medicinal plant. Fauzia Karim Shoma B. Pharmacy 2018-12-03T04:05:40Z 2018-12-03T04:05:40Z 2018 2017-07 Project report ID 12146006 http://hdl.handle.net/10361/10936 en BRAC University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 71 pages application/pdf BRAC University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Hygrophila schulli Phytochemical screening |
| spellingShingle |
Hygrophila schulli Phytochemical screening Shoma, Fauzia Karim Phytochemical screening and biological activity evaluation of Hygrophila schulli |
| description |
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. |
| author2 |
Rahman, Monica Sharfin |
| author_facet |
Rahman, Monica Sharfin Shoma, Fauzia Karim |
| format |
Project report |
| author |
Shoma, Fauzia Karim |
| author_sort |
Shoma, Fauzia Karim |
| title |
Phytochemical screening and biological activity evaluation of Hygrophila schulli |
| title_short |
Phytochemical screening and biological activity evaluation of Hygrophila schulli |
| title_full |
Phytochemical screening and biological activity evaluation of Hygrophila schulli |
| title_fullStr |
Phytochemical screening and biological activity evaluation of Hygrophila schulli |
| title_full_unstemmed |
Phytochemical screening and biological activity evaluation of Hygrophila schulli |
| title_sort |
phytochemical screening and biological activity evaluation of hygrophila schulli |
| publisher |
BRAC University |
| publishDate |
2018 |
| url |
http://hdl.handle.net/10361/10936 |
| work_keys_str_mv |
AT shomafauziakarim phytochemicalscreeningandbiologicalactivityevaluationofhygrophilaschulli |
| _version_ |
1814309036147867648 |