Effects of different polymers on thermal inkjet printing of oral thin films: a novel approach
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018.
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| Język: | English |
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BRAC University
2018
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| Dostęp online: | http://hdl.handle.net/10361/10830 |
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10361-10830 |
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10361-108302019-09-30T05:56:01Z Effects of different polymers on thermal inkjet printing of oral thin films: a novel approach Ahmed, Rubaiat Alam, Marzia Department of Pharmacy, BRAC University Polymer This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. Catalogued from PDF version of project report. Includes bibliographical references (page 43-48). The aim of this research was to use inkjet printing technology in formulation of personalized medicine. Thus in this research, an attempt was made to print OTF by TIJ printing. A placebo solution comprising of different polymers and polymer concentrations was used for TIJ printing on A4 paper. The formulations F1, F2, F3, F4, F5, F6, F7, F8, F9, F10, F11, F12 and F13 were prepared with the following compositions: (20% Glycerin+0.5% CMC+H₂O), (30% Glycerin+4% CMC+H₂O), (20% Glycerin+ 2% CMC+H₂O), (20% Glycerin+2%Gelatin+H₂O), (18% Glycerin+4% Gelatin+H₂O), (21% Glycerin+3.5% Gelatin+H₂O), (20% Glycerin+2% HPMC K4 MCR +H₂O), (12.5% Glycerin+1.25% HPMC K4 MCR +H₂O), (9.5% Glycerin+0.5% HPMC K4 MCR +H₂O), (20% Glycerin+1% HPMC K4 MCR +H₂O), (0.05% HPMC K4 MCR +49.98% H₂O+ 49.98% Ethanol) and (1% HPMC K4 MCR +H₂O) respectively. The placebo formulations were prepared by using glycerin as plasticizer and three different polymers; Carboxymethyl Cellulose (CMC), Gelatin and Hydroxypropyl Methyl Cellulose K4MCR (HPMC K4MCR) in different concentrations as film forming agents. The plasticizer and polymers were dissolved in aqueous solvent to prepare each placebo formulation with which the printer cartridge was refilled. Printing was done with the formulations using Canon PIXMA ip2772 thermal inkjet printer. F1 and F4 formulations, prepared with CMC and gelatin provided better imprint on paper at concentrations 0.5% and 2%, respectively. However, formulations prepared with HPMC K4MCR at a concentration as low as 0.05%, could not be jetted through the nozzle of the cartridge and no imprint could be obtained. Thus, from the study it was found that viscosity of the ink solutions affected the imprint quality. Rubaiat Ahmed B. Pharmacy 2018-11-08T09:31:53Z 2018-11-08T09:31:53Z 2018 2018-09 Project report ID 13146043 http://hdl.handle.net/10361/10830 en BRAC University project reports are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 48 pages application/pdf BRAC University |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Polymer |
| spellingShingle |
Polymer Ahmed, Rubaiat Effects of different polymers on thermal inkjet printing of oral thin films: a novel approach |
| description |
This project report is submitted in partial fulfilment of the requirements for the degree of Bachelor of Pharmacy, 2018. |
| author2 |
Alam, Marzia |
| author_facet |
Alam, Marzia Ahmed, Rubaiat |
| format |
Project report |
| author |
Ahmed, Rubaiat |
| author_sort |
Ahmed, Rubaiat |
| title |
Effects of different polymers on thermal inkjet printing of oral thin films: a novel approach |
| title_short |
Effects of different polymers on thermal inkjet printing of oral thin films: a novel approach |
| title_full |
Effects of different polymers on thermal inkjet printing of oral thin films: a novel approach |
| title_fullStr |
Effects of different polymers on thermal inkjet printing of oral thin films: a novel approach |
| title_full_unstemmed |
Effects of different polymers on thermal inkjet printing of oral thin films: a novel approach |
| title_sort |
effects of different polymers on thermal inkjet printing of oral thin films: a novel approach |
| publisher |
BRAC University |
| publishDate |
2018 |
| url |
http://hdl.handle.net/10361/10830 |
| work_keys_str_mv |
AT ahmedrubaiat effectsofdifferentpolymersonthermalinkjetprintingoforalthinfilmsanovelapproach |
| _version_ |
1814309555606126592 |