Frequency of Hepatitis B, C and HIV infections among transfusion-dependent Thalassemia patients in Bangladesh
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Science in Biotechnology, 2018.
| প্রধান লেখক: | |
|---|---|
| অন্যান্য লেখক: | |
| বিন্যাস: | গবেষণাপত্র |
| ভাষা: | English |
| প্রকাশিত: |
BRAC Univeristy
2018
|
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | http://hdl.handle.net/10361/10594 |
| id |
10361-10594 |
|---|---|
| record_format |
dspace |
| spelling |
10361-105942019-09-30T05:04:31Z Frequency of Hepatitis B, C and HIV infections among transfusion-dependent Thalassemia patients in Bangladesh Amatullah, Jumanah Siddique, Romana Mannoor, Dr. Md. Kaiissar Department of Mathematics and Natural Sciences, BRAC University Hepatitis B Hepatitis C HIV Thalassemia This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Science in Biotechnology, 2018. Cataloged from PDF version of thesis. Includes bibliographical references (page 34-36). Transfusion transmitted infections (TTI) have become a major problem in patients with thalassemia who have to undergo regular transfusion. Though effective screening system and proper donor selection have lowered the rate of infections, still the multitransfused patients are not risk free. In this study, a total of 148 transfusion-dependent (TD) patients with Beta Thalassemia was screened and among them infected cases with HCV, HBV and HIV were 12.83%, 3.37% and 0%, respectively. Moreover, 2.02% patients were found to be co-infected with both HBV and HCV. Immunochromatographic (ICT)-based rapid test kits are usually used to screen these infections in the donors’ blood before transfusion. However, the traditional ICT kits are not sensitive enough to detect infections. So, combination of both Nucleic Acid testing (NAT) and serological testing may be done to significantly reduce the risk of viral infections during blood transfusion. Besides, although HCV infections are most prevalent among maultitransfused patients, an effective vaccination system may reduce the rate of occurrences. Jumanah Amatullah B. Biotechnology 2018-09-16T10:55:31Z 2018-09-16T10:55:31Z 2018 2018-07 Thesis ID 13236011 http://hdl.handle.net/10361/10594 en BRAC University theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. 37 pages application/pdf BRAC Univeristy |
| institution |
Brac University |
| collection |
Institutional Repository |
| language |
English |
| topic |
Hepatitis B Hepatitis C HIV Thalassemia |
| spellingShingle |
Hepatitis B Hepatitis C HIV Thalassemia Amatullah, Jumanah Frequency of Hepatitis B, C and HIV infections among transfusion-dependent Thalassemia patients in Bangladesh |
| description |
This thesis is submitted in partial fulfilment of the requirements for the degree of Bachelor of Science in Biotechnology, 2018. |
| author2 |
Siddique, Romana |
| author_facet |
Siddique, Romana Amatullah, Jumanah |
| format |
Thesis |
| author |
Amatullah, Jumanah |
| author_sort |
Amatullah, Jumanah |
| title |
Frequency of Hepatitis B, C and HIV infections among transfusion-dependent Thalassemia patients in Bangladesh |
| title_short |
Frequency of Hepatitis B, C and HIV infections among transfusion-dependent Thalassemia patients in Bangladesh |
| title_full |
Frequency of Hepatitis B, C and HIV infections among transfusion-dependent Thalassemia patients in Bangladesh |
| title_fullStr |
Frequency of Hepatitis B, C and HIV infections among transfusion-dependent Thalassemia patients in Bangladesh |
| title_full_unstemmed |
Frequency of Hepatitis B, C and HIV infections among transfusion-dependent Thalassemia patients in Bangladesh |
| title_sort |
frequency of hepatitis b, c and hiv infections among transfusion-dependent thalassemia patients in bangladesh |
| publisher |
BRAC Univeristy |
| publishDate |
2018 |
| url |
http://hdl.handle.net/10361/10594 |
| work_keys_str_mv |
AT amatullahjumanah frequencyofhepatitisbcandhivinfectionsamongtransfusiondependentthalassemiapatientsinbangladesh |
| _version_ |
1814307985272340480 |