MARC details
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pam a22 i 4500 |
| 001 - CONTROL NUMBER |
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AALScienceDirectebook000009 |
| 003 - CONTROL NUMBER IDENTIFIER |
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BD-DhAAL |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20191205134905.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION |
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m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr cnu|||unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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150928s2016 ne ob 001 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
0081001142 |
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| International Standard Book Number |
9780081001141 |
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| Cancelled/invalid ISBN |
0081000944 |
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| Cancelled/invalid ISBN |
9780081000946 |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(OCoLC)922323918 |
| Canceled/invalid control number |
(OCoLC)922918604 |
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(OCoLC)929521751 |
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(OCoLC)932328797 |
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(OCoLC)951666431 |
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(OCoLC)1066557439 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
BD-DhAAL |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
RM301.25 |
| 060 00 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
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| Classification number |
2015 L-371 |
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| Classification number |
QV 38 |
| 072 #7 - SUBJECT CATEGORY CODE |
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| Subject category code |
MED |
| Subject category code subdivision |
071000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
615.1901 |
| Edition number |
23 |
| 245 00 - TITLE STATEMENT |
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| Title |
Concepts and models for drug permeability studies : |
| Remainder of title |
cell and tissue based In vitro culture models / |
| Statement of responsibility, etc |
edited by Bruno Sarmento. |
| Medium |
[electronic resource] |
| 260 #1 - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
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| Place of publication, distribution, etc |
Amsterdam : |
| Name of publisher, distributor, etc |
Elsevier, |
| Date of publication, distribution, etc |
2016. |
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| Date of publication, distribution, etc |
�2016 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 online resource. |
| 490 1# - SERIES STATEMENT |
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| Series statement |
Woodhead Publishing series in biomedicine ; |
| Volume number/sequential designation |
number 79 |
| 500 ## - GENERAL NOTE |
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| General note |
<strong>Off-Campus Access:</strong> Athens ID and Password Required |
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| General note |
<strong>On-Campus Access:</strong> No User ID or Password Required |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Front Cover; Related titles; Concepts and Models for Drug Permeability Studies; Copyright; Contents; List of contributors; List of figures; List of tables; 1 -- Introduction; 1.1 Introduction; References; 2 -- Importance and applications of cell- and tissue-based in vitro models for drug permeability screening in early stages o ...; 2.1 Introduction; 2.2 General considerations; 2.3 Drug transport; 2.3.1 Transport mechanisms; 2.4 Permeability-absorption models; 2.4.1 Physicochemical methods; 2.4.1.1 Physicochemical factors; 2.4.1.2 Immobilized artificial membrane chromatography |
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| Formatted contents note |
2.4.1.3 Parallel artificial membrane permeability assay2.4.2 In vitro cell and tissue methods; 2.4.2.1 Cell-based methods; 2.4.2.2 Tissue-based methods; Diffusion chambers; Franz cells; Everted sacs; Isolated membrane vesicles; 2.5 Methods for permeability calculation; 2.6 Standardization of protocols for in vitro methods; 2.7 The "three Rs" principle; 2.8 Biosecurity systems; References; 3.1 -- Cell-based in vitro models for buccal permeability studies; 3.1.1 Introduction; 3.1.2 Physiology of the buccal mucosa; 3.1.3 Different in vitro models; 3.1.3.1 Hamster cheek pouch cells |
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| Formatted contents note |
3.1.3.2 TR146 cell line3.1.3.2.1 Protocol; Cell culture conditions; Permeability studies; 3.1.3.3 Human oral keratinocytes; 3.1.3.3.1 Protocol; Oral keratinocyte culture conditions; Culturing on dead de-epidermized dermis (DDED); Permeability studies; 3.1.3.4 MatTek EpiOral"; 3.1.3.4.1 Protocol; Cell culture conditions; Permeability studies; 3.1.4 Conclusions; References; 3.2 -- Cell-based in vitro models for gastric permeability studies; 3.2.1 The stomach as a natural barrier to absorption; 3.2.2 Gastric drug delivery; 3.2.2.1 Molecular absorption in the stomach |
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| Formatted contents note |
3.2.2.2 Physicochemical factors mediating stomach absorptive permeability3.2.3 Cellularized models of gastric permeability; 3.2.3.1 Protocol for establishing cellularized artificial models of the gastric wall; 3.2.4 Conclusions; Acknowledgments; References; 3.3 -- Cell-based in vitro models for intestinal permeability studies; 3.3.1 Anatomy and physiology of human small intestine; 3.3.1.1 Stromal-epithelial cross-talk; 3.3.2 Mechanisms of transport; 3.3.3 Intestinal barriers; 3.3.4 Intestinal in vitro models; 3.3.4.1 Caco-2 model; 3.3.4.1.1 Accelerated Caco-2 models |
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| Formatted contents note |
3.3.4.1.2 Alternatives to the Caco-2 model3.3.4.2 Caco-2/HT29-MTX model; 3.3.4.3 Caco-2/Raji B model; 3.3.4.4 Caco-2/HT29-MTX/Raji B; 3.3.4.5 Novel 3D in vitro models; 3.3.5 Validation studies; 3.3.6 Conclusions; References; 3.4 -- Cell-based in vitro models for nasal permeability studies; 3.4.1 Introduction; 3.4.2 Nasal primary cell culture models; 3.4.2.1 Sampling approaches and procedures; 3.4.2.2 HNE cell preparation and culture initiation; 3.4.3 Immortalized nasal cell lines; 3.4.3.1 RMPI 2650 cell line; 3.4.3.2 BT cell line; 3.4.3.3 Human lung carcinoma cell line |
| 506 ## - RESTRICTIONS ON ACCESS NOTE |
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| Terms governing access |
Electronic access restricted to authorized BRAC University faculty, staff and students |
| 538 ## - SYSTEM DETAILS NOTE |
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| System details note |
Mode of access: Internet |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
Cell culture. |
| 9 (RLIN) |
38039 |
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| Topical term or geographic name as entry element |
Drugs |
| General subdivision |
Physiological transport |
| -- |
Research |
| -- |
Methodology. |
| 9 (RLIN) |
38040 |
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| Topical term or geographic name as entry element |
Drugs |
| General subdivision |
Testing. |
| 9 (RLIN) |
38041 |
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| Topical term or geographic name as entry element |
Epithelial cells. |
| 9 (RLIN) |
38042 |
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| Topical term or geographic name as entry element |
Cell culture. |
| Source of heading or term |
fast |
| 9 (RLIN) |
38039 |
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| Topical term or geographic name as entry element |
Drugs |
| General subdivision |
Testing. |
| Source of heading or term |
fast |
| 9 (RLIN) |
38041 |
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| Topical term or geographic name as entry element |
Epithelial cells. |
| Source of heading or term |
fast |
| 9 (RLIN) |
38042 |
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| Topical term or geographic name as entry element |
MEDICAL / Pharmacology |
| Source of heading or term |
bisacsh |
| 9 (RLIN) |
38043 |
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| Topical term or geographic name as entry element |
Permeability. |
| 9 (RLIN) |
38044 |
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| Topical term or geographic name as entry element |
Pharmacokinetics. |
| 9 (RLIN) |
38045 |
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| Topical term or geographic name as entry element |
Cell Culture Techniques. |
| 9 (RLIN) |
38046 |
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| Topical term or geographic name as entry element |
Models, Biological. |
| 9 (RLIN) |
38047 |
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| Topical term or geographic name as entry element |
Pharmaceutical Preparations |
| General subdivision |
metabolism. |
| 9 (RLIN) |
38048 |
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| Topical term or geographic name as entry element |
Tissue Culture Techniques. |
| 9 (RLIN) |
38049 |
| 655 #0 - INDEX TERM--GENRE/FORM |
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| Genre/form data or focus term |
Electronic books. |
| -- |
38050 |
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| Genre/form data or focus term |
Electronic books. |
| -- |
38050 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Sarmento, Bruno, |
| Relator term |
editor. |
| 9 (RLIN) |
38051 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Display text |
Print version: |
| International Standard Book Number |
9780081000946 |
| -- |
0081000944 |
| Record control number |
(OCoLC)911073450 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
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| Uniform title |
Woodhead Publishing series in biomedicine ; |
| Volume number/sequential designation |
no. 79. |
| 9 (RLIN) |
38052 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Public note |
Full text available on ScienceDirect |
| Uniform Resource Identifier |
<a href="http://www.sciencedirect.com/science/book/9780081000946">http://www.sciencedirect.com/science/book/9780081000946</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Dewey Decimal Classification |
| Item type |
E-Book |
