Principles of gene manipulation and genomics /

Primrose, S. B.

Principles of gene manipulation and genomics / S.B. Primrose and R.M. Twyman. - 7th edition - New Delhi ; Hoboken, NJ : Blackwell Publishing, c2006 [reprint 2014] - xxii, 644 pages : illustrations ; 28 cm.

Rev. ed. of: Principles of gene manipulation.7th ed. 2006 and Principles of genome analysis and genomics / Sandy B. Primrose, Richard M. Twyman.. 6th ed. 2001.3rd ed. 2003.

Includes bibliographical references (pages [547]-626) and index.

Gene manipulation in the post-genomics era -- Basic techniques -- Cutting and joining DNA molecules -- Basic biology of plasmid and phage vectors -- Cosmids, phasmids, and other advanced vectors -- Gene cloning strategies -- Sequencing genes and short stretches of DNA -- Changing genes : site-directed mutagenesis and protein engineering -- Bioinformatics -- Cloning in bacteria other than Escherichia coli -- Cloning in Saccharomyces cerevisiaea and other fungi -- Gene transfer to animal cells -- Genetic manipulation of animals -- Gene transfer to plants -- Advanced transgenic technology -- The organization and structure of genomes -- Mapping and sequencing genomes -- Comparative genomics -- Large-scale mutagenesis and interference -- Analysis of the transcriptome -- Proteomics I : expression analysis and characterization of proteins -- Proteomics II : analysis of protein structures -- Proteomics III : protein interactions -- Metabolomics and global biochemical networks -- Applications of genomics : understanding the basis of polygenic disorders and identifying quantitative trait loci -- Applications of recombinant DNA technology.

1405135441 (pbk. : alk. paper) 9788126548392

2005018202

QH442 / .O42 2006

660.65

QH442 / .O42 2006

2006 H-690 QH 442 / P952pa 2006